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ProteomicstRNA binding to KEOPS human protein complex
N6-theronylcarbomyl adenosine (t6A) is a universal tRNA posttranscriptional modification that promotes translation fidelity and is therefore required for the fitness of virtually all living cells. Kae1, the t6A modifying enzyme in eukaryotes and archea, resides within the KEOPS complex with three au...
ORGANISM(S): Homo sapiens (Human) 
2020-12-11 | PXD018007 | Pride
Trna Keops Hx-ms 
TranscriptomicsTranscription profiling of Saccharomyces cerevisiae KEOPS complex knockouts
Non-essential knockouts of KEOPS complex members and associated genes have been investigated by expression profiling.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-05 | E-TABM-1070 | biostudies-arrayexpress
GenomicsKEOPS 2 Metatranscriptomes
KEOPS-2
PRJEB30315 | ENA
TranscriptomicsUnravelling the pathobiological role of the fungal KEOPS complex in Cryptococcus neoformans
The kinase, putative endopeptidase and other peptides of small size (KEOPS) complex plays critical cellular functions in eukaryotes, but its pathobiological roles remains elusive in fungal pathogens. Here we comprehensively analyze the pathobiological functions of the KEOPS complex in fungal meningo...
ORGANISM(S): Cryptococcus neoformans 
2022-10-18 | GSE208333 | GEO
UnknownKEOPS complex promotes homologous recombination via DNA resection.
Not available
S-EPMC6582355 | biostudies-literature
UnknownA substrate binding model for the KEOPS tRNA modifying complex.
Not available
S-EPMC7718258 | biostudies-literature
ProteomicsIdentification of proteins interacting with KaeA, the subunit of KEOPS complex in Aspergillus nidulans in vivo.
The Kae1/KaeA protein is a subunit of the highly evolutionarily conserved KEOPS complex (Kinase, Endopeptidase and Other Proteins of Small size). The Kae1/KaeA gene has been identified in all previously sequenced genomes of Archea, Bacteria and Eucaryota, except for the most reduced genomes. The KEO...
ORGANISM(S): Emericella nidulans (Aspergillus nidulans) 
2023-03-11 | PXD034554 | Pride
Aspergillus nidulans Interactomics 
UnknownMolecular basis of A. thaliana KEOPS complex in biosynthesizing tRNA t6A.
Not available
S-EPMC11077089 | biostudies-literature
UnknownKEOPS complex expression in the frontal cortex in major depression and schizophrenia.
Not available
S-EPMC8005497 | biostudies-literature
GenomicsNuclear functions of KaeA, the subunit of KEOPS complex in Aspergillus nidulans.
Nuclear functions of KaeA, the subunit of KEOPS complex in Aspergillus nidulans.
PRJNA852273 | ENA
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