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TranscriptomicsExpression data from MSC-treated monocytes
Chronic inflammation leading to pro-inflammatory macrophage infiltration contributes to the pathogenesis of type 2 diabetes and subsequently the development of diabetic nephropathy. Mesenchymal stem cells (MSCs) possess unique immunomodulatory and cytoprotective properties making them an ideal candi...
ORGANISM(S): Homo sapiens 
2015-11-10 | E-GEOD-65561 | biostudies-arrayexpress
GenomicsAge-dependent changes in the LPS-induced transcriptome of bovine dermal fibroblasts occurs without major changes in the methylome
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Bos taurus 
2014-12-23 | E-GEOD-61168 | biostudies-arrayexpress
TranscriptomicsBradyrhizobium japonicum_Bacteroids Time Course
A time-course transcriptomic analysis of bacteroids isolated from soybean plants inoculated with B. japonicum USDA 110, relative to cells cultured in HM-arabinose medium was performed to characterize senescence genes. Four independent biological materials for bacteroids and free-living cells at 6 ti...
ORGANISM(S): Bradyrhizobium diazoefficiens USDA 110 
2014-11-01 | E-GEOD-60465 | biostudies-arrayexpress
TranscriptomicsRole of epigenetic modifiers on the bovine fibroblast innate immune response
The innate immune signaling pathway plays a crucial role in the recognition and early response to pathogens associated with disease. Genetic analysis has been unable to completely account for individual variability in the strength of the innate immune response. The aim of this study was to determine...
ORGANISM(S): Bos taurus 
2014-01-01 | E-GEOD-50405 | biostudies-arrayexpress
UnknownMolecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma.
Not available
S-EPMC6369924 | biostudies-literature
TranscriptomicsBradyrhizobium japonicum_Bacteroids vs. Bacteria grown in HM-Arabinose
A transcriptomic analysis of bacteroids isolated from soybean plants inoculated with B. japonicum USDA 110, relative to cells cultured in HM-arabinose medium was performed and the results combined with two other transcriptomic analyses to form a reiterated pool of transcripts that define genes essen...
ORGANISM(S): Bradyrhizobium diazoefficiens USDA 110 
2014-11-01 | E-GEOD-60279 | biostudies-arrayexpress
GenomicsComprehensive analysis of orphan CpG islands identifes novel promoters with conserved DNA methylation dynamics
We report the application of single molecule-based sequencing technology in combination with CXXC affinity purifcation (CAP-seq), MBD affinity purification (MAP-seq) and chromatin immunoprecipitation (ChIP-seq) to generate reciprocal methylation and chromatin modifcation maps in human and mouse. We ...
ORGANISM(S): Mus musculus 
2010-10-04 | E-GEOD-21442 | biostudies-arrayexpress
UnknownGenetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis.
Not available
S-EPMC4879695 | biostudies-literature
UnknownDiagnostic implications of review-of-systems questionnaires to differentiate epileptic seizures from psychogenic seizures.
Not available
S-EPMC5423814 | biostudies-literature
TranscriptomicsTranscriptomic response of bovine dermal fibroblasts to lipopolysaccharide
We report the responsiveness of bovine dermal fibroblasts to lipopolyssacharide (LPS) within individuals at different ages. Cultures were collected from three different heifers at the ages of approximately 5 and 16 months. Isolated fibroblasts were then exposed to LPS to determine whether there was ...
ORGANISM(S): Bos taurus 
2014-12-23 | E-GEOD-61027 | biostudies-arrayexpress
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