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UnknownCalcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer.
Not available
S-EPMC4644680 | biostudies-literature
UnknownThe CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth.
Not available
S-EPMC4188417 | biostudies-literature
OtherThe yeast La related protein Slf1p is a key activator of translation during the oxidative stress response.
Data from ProteomeXchange, PXD ID: PXD000887. File: 20131025_GP_CK_S2_1in10_01.mzml. Published as part of PLoS Genet. 2015 Jan 8;11(1):e1004903 . From the Abstract: {{i}} The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Slf1p and Sro9p are ...
ORGANISM(S): Yeast 
GPM32310018418 | GPMDB
Resource Reanalysis 
TranscriptomicsAnalysis of the role of yeast Slf1p in translation of specific mRNAs during oxidative stress response
The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Slf1p is an atypical La motif containing protein (LARP). LARPs are members of a superfamily of RNA-binding proteins conserved across eukaryotes. We performed transcriptomics and RIP-Seq analys...
ORGANISM(S): Saccharomyces cerevisiae 
2015-05-01 | E-MTAB-2567 | biostudies-arrayexpress
TranscriptomicsAnalysis of the role of yeast Sro9p in controlling the translation of specific mRNAs
The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Sro9p is an atypical La motif containing protein (LARP). LARPs are members of a superfamily of RNA-binding proteins conserved across eukaryotes. We performed transcriptomics and RIP-Seq analys...
ORGANISM(S): Saccharomyces cerevisiae 
2015-05-01 | E-MTAB-2568 | biostudies-arrayexpress
TranscriptomicsExpression data from AsPC1 cells treated with ICG-001
The CREB binding protein inhibitor ICG-001 suppresses pancreatic cancer growth We used microarrays to detail global gene expression changes in the pancreatic cancer cell line AsPC1 following treatment with ICG-001 or siRNA-mediated knockdown of CTNNB1 (beta-catenin) AsPC1 cells were treated with 10u...
ORGANISM(S): Homo sapiens 
2014-07-15 | E-GEOD-57728 | biostudies-arrayexpress
UnknownEvidence for the Association Between Adverse Childhood Family Environment, Child Abuse, and Caregiver Warmth and Cardiovascular Health Across the Lifespan: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.
Not available
S-EPMC11078262 | biostudies-literature
ProteomicsProteomics analysis of the effect of deletion of PUF3 on yeast via LC-MSMS.
The Puf family of RNA-binding proteins regulate the expression of genes by controlling protein synthesis or stimulating RNA decay. Puf3p is one of six Puf-family members in Saccharomyces cerevisiae. Puf3p has been characterised previously as regulating mRNA decay of nuclear mRNAs that encode for mi...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-04-13 | PXD001903 | Pride
Lc-msms Yeast Label-free quantification 
ProteomicsProteomics analysis of the effect of deletion and mutation of eIF4E binding proteins Caf20 and Eap1 on yeast via LC-MSMS.
There are multiple translational control pathways. These include pathways involving eIF4E binding proteins (4E-BPs), which inhibit translation by binding and sequestering the 5’ cap binding protein eIF4E away from its partner eIF4G. Saccharomyces cerevisiae has two 4E-BPs: Caf20p and Eap1p; and, mic...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-05-04 | PXD001348 | Pride
Lc-msms Yeast Label-free quantification 
ProteomicsIdentification of protein-protein interactions involving the eIF4E binding proteins Caf20p and Eap1p on yeast via affinity purification and LC-MSMS.
There are multiple translational control pathways. These include pathways involving eIF4E binding proteins (4E-BPs), which inhibit translation by binding and sequestering the 5’ cap binding protein eIF4E away from its partner eIF4G. Saccharomyces cerevisiae has two 4E-BPs: Caf20p and Eap1p. Previou...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-06-29 | PXD001407 | Pride
Lc-msms Affinity purification Yeast Label-free quantification 
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