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ProteomicsA pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease
Addona TA, Shi X, Keshishian H, Mani DR, Burgess M, Gillette MA, Clauser KR, Shen D, Lewis GD, Farrell LA, Fifer MA, Sabatine MS, Gerszten RE, Carr SA. Nat Biotechnol. 2011, 29(7):635-43. doi: 10.1038/nbt.1899. PMCID:PMC3366591. Discovery, AIMS, and MRM datasets Discovery_Tranche_hash: b/quYtp/Q8fY...
2013-12-19 | MSV000078513 | MassIVE
UnknownMultiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury.
Not available
S-EPMC4563722 | biostudies-literature
ProteomicsOptimized liquid and gas phase fractionations increase HLA-peptidome coverage for primary cell and tissue samples
Mass spectrometry is the most effective method to directly identify peptides presented on HLA molecules. However, current standard approaches often require billions of cells for input material to achieve high coverage of the immunopeptidome and are therefore not compatible with the often limiting am...
ORGANISM(S): Homo Sapiens 
2021-08-30 | PXD027165 | panorama
ProteomicsTAILS identifies candidate substrates and biomarkers of ADAMTS7, a therapeutic protease target in coronary artery disease
MacDonald BT, Keshishian H, Mundorff CC, Arduini A, Lai D, Bendinelli K, Popp NR, Bhandary B, Clauser KR, Specht H, Elowe NH, Laprise D, Xing Y, Kaushik VK, Carr SA, Ellinor PT. Loss-of-function mutations in the secreted enzyme ADAMTS7 (a disintegrin and metalloproteinase with thrombospondin motifs ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-03 | MSV000088508 | MassIVE
ProteomicsHighly multiplexed quantitative phosphosite assay for biology and preclinical studies
Reliable methods to quantify dynamic signaling changes across diverse pathways are needed to better understand the effects of disease and drug treatment in cells and tissues but are presently lacking. Here we present SigPath, a targeted mass spectrometry (MS) assay that measures 284 phosphosites in ...
ORGANISM(S): Homo Sapiens 
2021-10-08 | PXD026939 | panorama
OtherMultiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury.
Data from Massive, ID: MSV000078918. Experiment: Discovery_inPatient_IgY14_Supermix_depletion, PMI_Patient1, file: G20121012_PMI_P24_SMdepl_iTRAQ_basicRP_fr23.mzml. Published as part of Mol Cell Proteomics. 2015 Feb 27 . From the Abstract: {{i}} We have developed a novel plasma protein analysis pla...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM11210037151 | GPMDB
ProteomicsSensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury
Not available
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-02-09 | MSV000079033 | MassIVE
ProteomicsIgY14_Supermix_depletion_PMI_P2_iTRAQ
IgY14/Supermix depletion, patient 2, iTRAQ
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005317 | PeptideAtlas
ProteomicsIgY14_depletion_PMI_P2_iTRAQ
IgY14 only depletion, patient 2, iTRAQ
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005314 | PeptideAtlas
ProteomicsIgY14_Supermix_depletion_PMI_P3_iTRAQ
IgY14/Supermix depletion, patient 3, iTRAQ
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005313 | PeptideAtlas
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