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ProteomicsProteomic Profiling of Cerebrospinal Fluid in Adult Rats with Compromised Lymphatic Drainage Using DIA-PASEF
The glymphatic system’s outflow of “dirty” brain fluids collects in the meningeal lymphatic vessels, which drain via lymphatic collectors primarily to the deep cervical lymph nodes (dcLN). It is unclear, however, whether lymphatic dcLN drainage is a prerequisite for normal cerebral homeostasis. Here...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-07-04 | PXD063161 | Pride
Cauterized Rat Dia-pasef 
ProteomicsLabel free-DDA nano-LC/MS/MS analysis of Human Mesenteric lymph collected from Inflammatory Bowel Disease (IBD) subjects.
Compromise of the intestinal barrier have been associated with a series of inflammatory conditions where the routine controls nutrient absorption and pathogens exclusion is lost to different degrees. The intestinal epithelial cells form a barrier of selective permeability which protects from invasio...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD044801 | Pride
Lable free-dda Lymphatics Inflammatory bowel disease Lymph 
ProteomicsTMT-Based Quantitative Proteomics of Cerebrospinal Fluid Reveals Molecular Signatures of Lymphatic Drainage Impairment in Young Rats
The glymphatic system facilitates the clearance of interstitial solutes and waste products from the brain parenchyma, channeling them into the meningeal lymphatic vessels for subsequent drainage into the deep cervical lymph nodes (dcLNs). However, the extent to which this lymphatic outflow via dcLNs...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-07-04 | PXD063564 | Pride
Dc-ln cauterization Csf 
UnknownSpatially resolved qualified sewage spot sampling to track SARS-CoV-2 dynamics in Munich - One year of experience.
Not available
S-EPMC8294104 | biostudies-literature
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