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GenomicsCpG island-mediated global gene regulatory modes in mouse embryonic stem cells
In order to identify the regions occupied by transcription factors, we performed bio-ChIP followed by massive parallel sequencing (bioChIP-Seq) in mouse ES cells. A total of seven DNA transcription factors including Myc module (Myc, Max, E2F4, Tip60 and Dmap1) and Core module transcription factors (...
ORGANISM(S): Mus musculus 
2014-11-24 | E-GEOD-48666 | biostudies-arrayexpress
TranscriptomicsApelin/APJ signaling mediated by G alpha 13 and MEF2 in endothelial cells
Evaluation of gene transcripts that are downstream of apelin/APJ signaling in HUVECs Duplicates per group, subjected to: 1) control siRNA, 2) MEF2A and MEF2C siRNA, 3) G alpha 13 siRNA, and 4) apelin and APJ siRNA
ORGANISM(S): Homo sapiens 
2013-05-11 | E-GEOD-46825 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of fibroblasts influenced by exosomes derived from melanoma cell line G-361
In this in-vitro study, we demonstrate the different effects of exosomes produced by melanoma cells on the functional properties of normal dermal fibroblasts and fibroblasts prepared from skin metastasis of CMM. Both normal and cancer-associated fibroblast were prepared by a)DMEM with 10% EDS (contr...
ORGANISM(S): Homo sapiens 
2022-12-31 | E-MTAB-10278 | biostudies-arrayexpress
UnknownNovel malformations: Chiari type 1 and hydrocephalus in Zhu-Tokita-Takenouchi-Kim syndrome and novel SON variants.
Not available
S-EPMC9755635 | biostudies-literature
ProteomicsComparative gene and protein expression profile of olfactory ensheathing cells from olfactory bulb and olfactory mucosa
Olfactory ensheathing cells are one of the few central nervous system regenerative cells discovered so far. It is characterized by its lifelong nerve regeneration function, and it can also release a variety of neurotrophic factors and neural adhesion molecules. It is considered to be the glial cell ...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD024046 | Pride
Olfactory ensheathing cells (oecs)  olfactory bulb (ob)  olfactory mucosa (om)  gene  protein  gene ontology (go)  kyoto encyclopedia of genes and genomes (kegg)  molecular function  cellular component  biological process 
UnknownAn intronic mutation c.6430-3C>G in the F8 gene causes splicing efficiency and premature termination in hemophilia A.
Not available
S-EPMC5965921 | biostudies-literature
ProteomicsTime-resolved combined analysis of transcriptome and proteome of the pathogenicity-activated plant pathogen Xanthomonas oryzae pv. oryzae
Xanthomonas oryzae pv. oryzae (Xoo) is a rice pathogen causing bacterial blight, which outbreaks in most rice cultivating countries and reduces yield up to 50% due to no effective pesticide. Urgent responses of Xoo upon the initial contacts with rice at infection site are essential for pathogenesis....
ORGANISM(S): Xanthomonas oryzae pv. oryzae KACC 10331 
2021-09-09 | PXD020135 | Pride
Transcriptome Time-resolved gene expression Xoo–rice interactions Pathogenicity Proteome Xanthomonas oryzae pv. oryzae 
UnknownAssociation of TNF-alpha G-308A gene polymorphism with depression: a meta-analysis.
Not available
S-EPMC5659227 | biostudies-literature
TranscriptomicsTranscription profiling of 4 prostate cancer cell lines treated with the DNA methyltransferase inhibitor 5-aza-dC
This microarray dataset accompanies the publication by Kim et al, "The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer". The dataset comprises four prostate cancer cell lines treated with the DNA methyltransferase inhibitor 5-aza-dC. For each cell line, gene...
ORGANISM(S): Homo sapiens 
2005-10-18 | E-SMDB-3416 | biostudies-arrayexpress
TranscriptomicsTemporal Control of Macrophage Pro-inflammatory Phenotype by a Biphasic HIF-1α Regulatory Program
Hypoxia-inducible factor 1α (HIF-1α) broadly orchestrates metabolic reprogramming in inflammatory macrophages. However, how HIF-1α is activated in the earliest events following pattern recognition receptor activation remains unclear. We found that HIF-1α is functionally active shortly after macroph...
ORGANISM(S): Mus musculus 
2026-07-13 | E-MTAB-16172 | biostudies-arrayexpress
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