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MetabolomicsTrans-tissue molecular coordination in high-intensity physical activity
High-intensity physical activity has major impacts in different parts of the body. However, the regulatory coordination between different tissues to support the high physical demands is poorly understood. Here we performed a multi-omics analysis of blood plasma, urine and saliva from a group of fire...
2025-07-03 | MTBLS1891 | MetaboLights
UnknownAn IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis.
Not available
S-EPMC11189607 | biostudies-literature
TranscriptomicsIntegrative AUF1 PAR-CLIP analysis uncovers AUF1 roles in translation and genome integrity (PAR-CLIP)
We report that AUF1 modulates global mRNA stability and translation, in turn promoting the maintenance of DNA integrity. Please see individual series. In short, for AUF1 PAR-CLIP, the four isoforms of AUF1 (p37, p40, p42, and p45) tagged with a Flag epitope were expressed in HEK293 cells. For total ...
ORGANISM(S): Homo sapiens 
2014-11-05 | E-GEOD-52971 | biostudies-arrayexpress
TranscriptomicsIntegrative AUF1 PAR-CLIP analysis uncovers AUF1 roles in translation and genome integrity (RNA-Seq 1)
We report that AUF1 modulates global mRNA stability and translation, in turn promoting the maintenance of DNA integrity. Please see individual series. For AUF1 PAR-CLIP, the four isoforms of AUF1 (p37, p40, p42, and p45) tagged with a Flag epitope were expressed in HEK293 cells. For total RNA-Seq HE...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-52973 | biostudies-arrayexpress
TranscriptomicsIntegrative AUF1 PAR-CLIP analysis uncovers AUF1 roles in translation and genome integrity (RNA-Seq 2)
We report that AUF1 modulates global mRNA stability and translation, in turn promoting the maintenance of DNA integrity. Please see individual series. In short, for AUF1 PAR-CLIP, the four isoforms of AUF1 (p37, p40, p42, and p45) tagged with a Flag epitope were expressed in HEK293 cells. For total ...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-52975 | biostudies-arrayexpress
Proteomics,MultiomicsLIQUID publication data - human plasma lipids
These files are associated with the publication of the LIQUID identification tool for lipid MS/MS spectra.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-11-28 | MSV000080359 | MassIVE
MetabolomicsIntegrated omics analysis of pathogenic host responses during pandemic H1N1 influenza virus infection: the crucial role of lipid metabolism
Pandemic influenza viruses modulate pro-inflammatory responses that can lead to immunopathogenesis. We present an extensive and systematic profiling of lipids, metabolites and proteins in respiratory compartments of ferrets infected with either 1918 or 2009 human pandemic H1N1 influenza viruses. Int...
2016-05-11 | MTBLS196 | MetaboLights
GenomicsGenome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

Monozygotic (MZ) twins have been widely employed for dissection of the relative contributions of genetics and environment in disease. In multiple sclerosis (MS), an autoimmune demyelinating disease that commonly causes neurodegeneration and disability in young adults, disease discordance in M...

phs000239.v2.p1 | EGA
ProteomicsMALDI informed microdissected airway proteomics
After performing MALDI metabolomics analysis, we identified airway regions. On a consecutive slide we used laser capture microdissection (LCM) to cut out regions of interest that had an airway specific signal by MALDI. The samples were prepped using the MicroPOTS protocol (PMID: 33491460) and analyz...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-10-20 | MSV000090561 | MassIVE
TranscriptomicsIntegrative AUF1 PAR-CLIP analysis uncovers AUF1 roles in translation and genome integrity (Ribosome)
We report that AUF1 modulates global mRNA stability and translation, in turn promoting the maintenance of DNA integrity. Please see individual series. In short, For AUF1 PAR-CLIP, the four isoforms of AUF1 (p37, p40, p42, and p45) tagged with a Flag epitope were expressed in HEK293 cells. For total ...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-52976 | biostudies-arrayexpress
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