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UnknownPhase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with advanced melanoma.
Not available
S-EPMC4879709 | biostudies-literature
TranscriptomicsTranscription profiling of human pancreatic carcinoma growing in the pancreas of nude mice
Using Affymetrix HG-U133-Plus 2.0 array and Laser Capture Microdissection techniques, we determined whether growth in different zones of the same tumor affected expression of genes by human pancreatic cancer cells. Human L3.6pl pancreatic cancer cells were implanted into the pancreas of nude mice. ...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7824 | biostudies-arrayexpress
UnknownBEAM: a randomized phase II study evaluating the activity of bevacizumab in combination with carboplatin plus paclitaxel in patients with previously untreated advanced melanoma.
Not available
S-EPMC4669379 | biostudies-literature
UnknownPhase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor.
Not available
S-EPMC4878037 | biostudies-literature
UnknownCombined BRAF (Dabrafenib) and MEK inhibition (Trametinib) in patients with BRAFV600-mutant melanoma experiencing progression with single-agent BRAF inhibitor.
Not available
S-EPMC4226803 | biostudies-literature
UnknownImatinib for melanomas harboring mutationally activated or amplified KIT arising on mucosal, acral, and chronically sun-damaged skin.
Not available
S-EPMC4878082 | biostudies-literature
TranscriptomicsAn Automated, High Platform for Induced Pluripotent Stem Cell Derivation, Characterization and Differentiation
Induced pluripotent stem cells (iPSCs) have become an essential tool for both modeling how causal genetic variants impact cellular function in disease, as well as being an emerging source of tissue for transplantation medicine. Unfortunately the preparation of somatic cells, their reprogramming and ...
ORGANISM(S): Homo sapiens 
2015-08-03 | E-GEOD-69868 | biostudies-arrayexpress
GenomicsNational Cancer Institute Genome-Wide Association Study of Renal Cell Carcinoma

The National Cancer Institute (NCI) genome-wide association study (GWAS) of renal cell carcinoma (RCC) was conducted to investigate common genetic variants associated with RCC risk. The GWAS includes 1,453 RCC cases and 3,531 controls of European background from 4 studies (3 cohort, 1 case-con...

phs000351.v1.p1 | EGA
TranscriptomicsGlobal gene expression analysis in cord blood reveals gender-specific differences in response to carcinogenic exposure in utero
Gender effects in the incidence of childhood cancers have been described but the aetiology still needs to be fully examined. Given the latent period of e.g. leukemia, its very early onset in childhood might indicate the foetal period as a critical period. We consequently hypothesize that gender-spec...
ORGANISM(S): Homo sapiens 
2012-06-26 | E-GEOD-31836 | biostudies-arrayexpress
ProteomicsPrimary human fibroblasts Proteome response to an icMERS coronavirus
Proteomics data from cell culture; time points 0, 12, 24, 36 & 48 h
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Middle East Respiratory Syndrome-related Coronavirus (ncbitaxon:1335626) 
2018-01-05 | MSV000081887 | MassIVE
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