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TranscriptomicsKnockout mice reveal key roles for claudin-18 in alveolar fluid homeostasis.
Claudin proteins are major constituents of epithelial and endothelial tight junctions (TJ), where they serve as regulators of paracellular permeability to ions and solutes. Claudin-18, a member of the large claudin family, is highly expressed in lung epithelium. To elucidate the role of claudin-18 i...
ORGANISM(S): Mus musculus 
2014-04-06 | E-GEOD-48443 | biostudies-arrayexpress
UnknownVitamin C Lowers Blood Pressure in Spontaneously Hypertensive Rats by Targeting Angiotensin-Converting Enzyme I Production in a Frequency-Dependent Manner
Not available
S-EPMC9286971 | biostudies-literature
UnknownA biological function based biomarker panel optimization process.
Not available
S-EPMC6517383 | biostudies-literature
ProteomicsProteomic analysis of human follicular fluid in poor ovarian responders during in vitro fertilization
Poor ovarian response (POR) observed in controlled ovarian stimulation (COS) is often observed during in vitro fertilization and embryo transfer (IVF-ET) cycles and is a major problem. A POR has been found to be related to several factors, including advanced age, high body mass index, and history of...
ORGANISM(S): Homo sapiens (Human) 
2018-07-05 | PXD005436 | Pride
Multiple reaction monitoring Follicular fluid Biomarker Proteomics Poor ovarian response 
ProteomicsLysine propionylation is a prevalent post-translational modification in Thermus thermophilus
Immunoaffinity purification with anti-propionyllysine antibody and nanoLC-MS/MS analysis
ORGANISM(S): Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
2019-11-28 | PXD000544 | Pride
Thermus thermophilus Lysine propionylation Posttranslational modification Lc-ms/ms 
ProteomicsAcetylome of Thermus thermophilus HB8
Lysine acetylation in proteins has recently been globally identified in bacteria and eukaryotes.  Even though acetylproteins are known to be involved in various cellular processes, its physiological significance has not yet been resolved.  Using a proteomics approach in combination with immunoprecip...
ORGANISM(S): Thermus thermophilus 
2020-01-22 | PXD000184 | Pride
T.thermophilus Acetylome Anti-acetyllysine antibody Lc-ms/ms 
TranscriptomicsThe role of the Ras- and cAMP-signaling pathways in stress response and sterol biosynthesis in Cryptococcus neoformans
The cAMP-pathway plays a central role in regulation of growth, differentiation, and virulence of human pathogenic fungi, including Cryptococcus neoformans. Three major upstream signaling regulators of the adenylyl cyclase (Cac1), Ras, Aca1 (Adenylyl cyclase-associated protein 1) and G-alpha subunit ...
ORGANISM(S): Cryptococcus neoformans var. grubii H99 
2010-05-22 | E-GEOD-17338 | biostudies-arrayexpress
Transcriptomicscps wild type vs cps mgtA mutant
Comparison of the Streptococcus pneumoniae D39 cps mgtA mutant vs cps wild type One condition design comparison of two strains including a dye swap
ORGANISM(S): Streptococcus pneumoniae D39 
2011-05-05 | E-GEOD-26154 | biostudies-arrayexpress
UnknownDistinct Profiles of Cell-Free MicroRNAs in Plasma of Veterans with Post-Traumatic Stress Disorder.
Not available
S-EPMC6678393 | biostudies-literature
TranscriptomicsmiR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4
we identified novel age-related microRNAs through comparative analysis of miRNA expression profiles in young and old myoblasts using next generation sequencing (NGS) small RNA profiles of young mouse and old mouse were generated by deep sequencing, in each four samples, using Illumina GAIIx
ORGANISM(S): Mus musculus 
2015-09-04 | E-GEOD-66267 | biostudies-arrayexpress
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