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MetabolomicsA Pathogen-Responsive Gene Cluster for Highly Modified Fatty Acids in Tomato
In response to biotic stress, plants produce suites of highly modified fatty acids that bear unusual chemical functionalities. Despite their chemical complexity and proposed roles in pathogen defense, little is known about the biosynthesis of decorated fatty acids in plants. Falcarindiol is a protot...
2022-01-17 | MTBLS1039 | MetaboLights
UnknownTechnical note: TROG 15.01 SPARK trial multi-institutional imaging dose measurement.
Not available
S-EPMC5875840 | biostudies-literature
UnknownPhase I First-in-Human Study of Venetoclax in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma.
Not available
S-EPMC5455685 | biostudies-literature
MetabolomicsLipid metabolites as potential diagnostic and prognostic biomarkers for acute community acquired pneumonia
Early diagnosis of acute community-acquired pneumonia (CAP) is important in patient triage and treatment decisions. To identify biomarkers that distinguish patients with CAP from non-CAP controls, we conducted an untargeted global metabolome analysis for plasma samples from142 patients with CAP (CAP...
2016-08-11 | MTBLS354 | MetaboLights
UnknownAssociation of atrial fibrillation and various cancer subtypes.
Not available
S-EPMC8485786 | biostudies-literature
UnknownNOTCH Signaling Limits the Response of Low-Grade Serous Ovarian Cancers to MEK Inhibition.
Not available
S-EPMC9716250 | biostudies-literature
ProteomicsMulti-omics and Network Evaluation of Arogenate Dehydratase Knock-out Mutants in Arabidopsis thaliana
By knocking out genes encoding specific arogenate dehydrase (ADT) enzymes in Arabidopsis, variable reductions in lignin can be achieved. To understand how ADT composition affects plant phenotypes and biomolecular systems, we successfully constructed single and multiple ADT knockout (KO) mutants in A...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
MSV000081518 | MassIVE
ProteomicsDiscovery of an ApoE4-Targeted Small-Molecule SirT1 Enhancer for the Treatment of Alzheimer’s Disease
Herein we describe the discovery of an orally brain-22 permeable small-molecule, DDL-218, that enhanced SirT1 in ApoE4-expressing neuronal cells 23 and a murine AD model. DDL-218 increased the transcription factor NFYb resulting in 24 upregulation of PRMT5. Mechanistic and modeling studies show that...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD060379 | Pride
Sirtuin 1 Prmt5 Nfyb Sirt1 Sirt1 enhancer Memory Apolipoprotein e4 
UnknownMulti-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity.
Not available
S-EPMC10557820 | biostudies-literature
UnknownRelationships of p16 Immunohistochemistry and Other Biomarkers With Diagnoses of Cervical Abnormalities: Implications for LAST Terminology.
Not available
S-EPMC8575174 | biostudies-literature
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