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Analysis of mRNA changes in HeLa cells following Ago2 or Dicer depletion. Dicer, a cytoplasmic RNase III, generates the mature form of small RNAs including microRNA. Ago2 is a component of an effector complex of microRNA. Keywords: gene expression array-based (RNA / in situ oligonucleotide) siRNA a...
ORGANISM(S): Homo sapiens 
In this study, we attempted to identify a new probiotic effector molecule of A. muciniphila that plays a role in modulating host cells through secretome analysis. We performed proteomic profiling of secretome of A. muciniphila cultivated under basal medium and BHI medium (supplemented with 0.2% muci...
ORGANISM(S): Akkermansia muciniphila ATCC BAA-835 
2024-03-14 | PXD042323 | Pride
Profilling normal human placantal proteomes using LTQ-OrbiTrap
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-10 | MSV000083950 | MassIVE
Human thyroid cancer cell line BCPAP was engineered for doxycyclin-mediated inducible expressoin of Prox1 and next generation sequcing was performed to study the transcriptional regulation by Prox1 BCPAP cells were infected with rTTA2 lentivirus. The resulting cell populations were then stably trans...
ORGANISM(S): Homo sapiens 
Circular RNAs (circRNAs) accumulate with age, but their functional impact on aging remains elusive. In this study, we reveal a mechanism by which ribonuclease κ (RNASEK) prevents age-dependent circRNA accumulation by promoting its degradation. Through a genetic screen targeting ribonucleases, we ide...
ORGANISM(S): Caenorhabditis Elegans 
2026-01-15 | PXD073097 |
Profilling normal human placantal proteomes using LTQ-OrbiTrap
ORGANISM(S): Homo sapiens (Human) 
2015-05-26 | PXD000754 | Pride
Parkinson’s disease (PD) is characterized by complex molecular and circuit-level alterations that extend beyond dopaminergic neurodegeneration, yet the spatial integration of metabolic and proteomic changes remains insufficiently explored. Here, we combined time-of-flight secondary ion mass spectrom...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-28 | PXD071834 | Pride
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