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TranscriptomicsExon arrays for human embryonic stem cells
Samples were used to study if genomic copy number variation changes detected with SNP 6.0 array would correlate with the expression level changes in human embryonic stem cells These samples were used as a portion of the study evaluating the genomic stability and its effects on human embryonic stem c...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-15095 | biostudies-arrayexpress
UnknownRole of long interspersed nuclear element-1 in the regulation of chromatin landscapes and genome dynamics.
Not available
S-EPMC8524765 | biostudies-literature
GenomicsLong range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X
Dosage compensation in D. melanogaster males is achieved via targeting of the MSL complex to X chromosomal genes. This is proposed to involve initial sequence-specific recognition of the X at ~150-300 chromatin entry sites, and subsequent spreading to nearby active genes. Here we test a model in whi...
ORGANISM(S): Drosophila melanogaster 
2009-08-20 | E-GEOD-17729 | biostudies-arrayexpress
UnknownManagement of Multi-Casualty Incidents in Mountain Rescue: Evidence-Based Guidelines of the International Commission for Mountain Emergency Medicine (ICAR MEDCOM).
Not available
S-EPMC6014052 | biostudies-literature
GenomicsSATAY sequencing data from multiple biological and technical replicates of Saccharomyces cerevisiae
Transposon insertion site sequencing (TIS) is a powerful tool that has significantly advanced our knowledge of functional genomics. While providing valuable insights, these applications of TIS focus on (conditional) gene essentiality and neglect possibly interesting but subtle differences in the imp...
ORGANISM(S): Saccharomyces cerevisiae 
2024-11-18 | E-MTAB-14476 | biostudies-arrayexpress
TranscriptomicsRNA polyadenylation landscape in human and mouse cells
Alternative polyadenylation (APA) of mRNAs has emerged as an important mechanism for post-transcriptional gene regulation in higher eukaryotes. Although microarrays have recently been used to characterize APA globally, they have a number of serious limitations that prevents comprehensive and highly ...
ORGANISM(S): Mus musculus 
2011-02-26 | E-GEOD-25450 | biostudies-arrayexpress
UnknownHigh-dose intravenous vitamin C combined with cytotoxic chemotherapy in patients with advanced cancer: a phase I-II clinical trial.
Not available
S-EPMC4388666 | biostudies-literature
UnknownIdentifying predictors of treatment response and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-negative breast cancer: the NEOENDO translational study.
Not available
S-EPMC11635665 | biostudies-literature
TranscriptomicsRNA-seq of murine small intestinal organoids treated with type I PRMT inhibitor MS023 against untreated controls
Murine small intestinal organoids were cultured in the presence or absence of 5µM inhibitor MS023 (PubChem CID 92136227), which targets type I protein arginine methyltransferases Prmt1, Prmt3, Prmt4, Prmt6, Prmt8. Organoids were grown in culture media containing EGF, Noggin and R-spondin (ENR), medi...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-9291 | biostudies-arrayexpress
TranscriptomicsRNA-seq of murine small intestinal organoids treated with Ep300/Crebbp inhibitor I-CBP112 against untreated controls
Murine small intestinal organoids were cultured in the presence or absence of 3µM inhibitor I-CBP112 (PubChem CID 90488984), which targets E1A Binding Protein P300 (Ep300) and Creb-binding protein (Crebbp, Cbp). Organoids were grown in culture media containing EGF, Noggin and R-spondin (ENR), media ...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-9290 | biostudies-arrayexpress
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