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UnknownIdentification of the remains of King Richard III.
Not available
S-EPMC4268703 | biostudies-literature
UnknownThe State of National Institute of Health Awards for funding genetic counseling research, resources, and training over the past decade.
Not available
S-EPMC11632580 | biostudies-literature
UnknownDeciphering the molecular adaptation of the king scallop (Pecten maximus) to heat stress using transcriptomics and proteomics.
Not available
S-EPMC4657243 | biostudies-literature
ProteomicsLysosomal alterations and altered electrophysiological activity in atypical juvenile neuronal ceroid lipofuscinoses (CLN3 1 kb deletion, E295K) patient-derived cortical neurons
Juvenile neuronal ceroid lipofuscinoses (JNCL) is a lysosomal storage disorder associated with fatal neurodegeneration that is caused by mutations in CLN3. Most individuals with JNCL carry at least one allele with 1 kb deletion in CLN3 which results in the deletion of exons 7 and 8. There is a need ...
ORGANISM(S): Homo sapiens (Human) 
2022-12-07 | PXD032191 | Pride
Lysosomal storage disorder Neurological disease models Juvenile neuronal ceroid lipofuscinoses Human induced pluripotent stem cells 
ProteomicsEffect of TDP-43 overexpression on neuron structure, function and proteome in vitro
Discovery of proteins and pathways affected by overexpression of the protein TDP-43 in neurons cultured from wild-type and mice homogygous for the transgene.
ORGANISM(S): Mus musculus (Mouse) 
2023-04-27 | PXD014889 | Pride
Cytoskeleton Neuroproteomics Amyotrophic lateral sclerosis Tdp-43 
ProteomicsEffects of TDP-43 overexpression on neuron proteome and morphology in vitro
Primary neuronal cultures were prepared from transgenic mice overexpressing wildtype human TDP-43 under the control of the prion promoter (hTDP-43Prp).
ORGANISM(S): Mus musculus (Mouse) 
2026-06-29 | PXD022671 | Pride
Proteomics Tdp-43 Als Ftd Neuron morphology 
ProteomicsTemporal changes in the microglial proteome of male and female mice after a diffuse brain injury using label-free quantitative proteomics
Traumatic brain injury (TBI) triggers neuroinflammatory cascades mediated by microglia, which promotes tissue repair in the short-term. These cascades may exacerbate TBI-induced tissue damage and symptoms in the months to years post-injury. However, the progression of the microglial function across ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD033628 | Pride
Proteomics Tbi Inflammation Biological sex Traumatic brain injury Microglia 
ProteomicsA microfluidic co-culture platform to generate synaptically separated networks that uncover the role of astrocytes in the initiation and progression of neuron pathology
Communication between astrocytes and neurons plays a pivotal role in the development, maintenance and dysfunction of cellular networks within the central nervous system. Further understanding the contribution of astrocytes to the initiation and progression of neuropathology has, however, been hinder...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-06-08 | PXD055523 | Pride
Astrocytes Proteomics Microfluidics Neuropathology 
UnknownMalaria parasites regulate intra-erythrocytic development duration via serpentine receptor 10 to coordinate with host rhythms.
Not available
S-EPMC7265539 | biostudies-literature
UnknownMaternal IgA protects against the development of necrotizing enterocolitis in preterm infants.
Not available
S-EPMC7424541 | biostudies-literature
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