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ProteomicsMap of the Kir2.1 interactome using BioID
Kir2.1, an inward rectifier potassium channel, plays an important role in controlling membrane potential specially in cardiomyocytes. Here we explore its interactome via proximity biotin labeling and affinity purification approach (BioID). First, BioID membrane controls were generated with randomly ...
ORGANISM(S): Homo sapiens (Human) 
2020-06-17 | PXD011004 | Pride
Kir2.1 Bioid Ats 
TranscriptomicsExpression data from yeast heterologously expressing alpha-ENaC, CFTR or Kir2.1 [Kir2.1]
Misfolded membrane proteins are retained in the endoplasmic reticulum (ER) and are subject to the ER associated degradation pathway, which clears the secretory pathway of potentially toxic species. While the transcriptional response to environmental stressors has been extensively studied, limited d...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-10 | E-GEOD-61245 | biostudies-arrayexpress
TranscriptomicsExpression data from yeast heterologously expressing alpha-ENaC, CFTR or Kir2.1 [CFTR]
Misfolded membrane proteins are retained in the endoplasmic reticulum (ER) and are subject to the ER associated degradation pathway, which clears the secretory pathway of potentially toxic species. While the transcriptional response to environmental stressors has been extensively studied, limited d...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-10 | E-GEOD-61244 | biostudies-arrayexpress
TranscriptomicsExpression data from yeast heterologously expressing alpha-ENaC, CFTR or Kir2.1 alpha-ENaC]
Misfolded membrane proteins are retained in the endoplasmic reticulum (ER) and are subject to the ER associated degradation pathway, which clears the secretory pathway of potentially toxic species. While the transcriptional response to environmental stressors has been extensively studied, limited d...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-10 | E-GEOD-61243 | biostudies-arrayexpress
UnknownKir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents.
Not available
S-EPMC8143648 | biostudies-literature
TranscriptomicsExpression data from yeast heterologously expressing αENaC, CFTR or Kir2.1 [Kir2.1]
Misfolded membrane proteins are retained in the endoplasmic reticulum (ER) and are subject to the ER associated degradation pathway, which clears the secretory pathway of potentially toxic species. While the transcriptional response to environmental stressors has been extensively studied, limited da...
ORGANISM(S): Schizosaccharomyces pombe Saccharomyces cerevisiae 
2014-09-10 | GSE61245 | GEO
UnknownESCRT regulates surface expression of the Kir2.1 potassium channel.
Not available
S-EPMC3890348 | biostudies-literature
UnknownPolarized localization of phosphatidylserine in the endothelium regulates Kir2.1.
Not available
S-EPMC10243826 | biostudies-literature
TranscriptomicsHigh-throughput sequencing Transcriptomes Analysis of WT and Kcnj2 KO mouse BMDMs treated with LPS or kir2.1 inhibitor
Purpose:Mouse BMDM is the universal cell type of studying innate immunity.This study was to analyze LPS induced innate immune response and the relationship between the inward rectifier potassium channel Kir2.1 and LPS induced innate immune respone Methods: WT and Kcnj2 KO BMDM cells were treated wit...
ORGANISM(S): Mus musculus 
2022-04-05 | GSE146158 | GEO
GenomicsHigh-throughput sequencing Transcriptomes Analysis of WT and Kcnj2 KO mouse BMDMs treated with LPS or kir2.1 inhibitor
High-throughput sequencing Transcriptomes Analysis of WT and Kcnj2 KO mouse BMDMs treated with LPS or kir2.1 inhibitor
PRJNA609623 | ENA
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