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TranscriptomicsTranscription profiling of human U927 cells polysomal and cytoplasmic RNA before and after PMA stimulation
Human histomonocytic U937 cells exhibit macrophage-like properties after phorbol ester stimulation. Accumulating evidence demonstrated that remarkable number of transcripts changed in their amount at total RNA levels. However, post-transcriptional regulation has not been fully elucidated in this m...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1783 | biostudies-arrayexpress
TranscriptomicsExpression data from murine follicular dendritic cells
Germinal centers (GCs) are clusters of activated B cells built on stromal cells known as follicular dendritic cells (FDCs). In the Peyer’s patches (PPs), GCs are chronically induced by bacteria and are the major sites for generation of gut IgA immune responses. Whether FDCs directly contribute to ...
ORGANISM(S): Mus musculus 
2010-07-30 | E-GEOD-19401 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse macrophage cell line Polysomal, free mRNP, and total cellular mRNA of before and after LPS stimulation
Bacterial lipopolysaccharide(LPS) dramatically activates macrophages. So far, dozen of papers indicated that many proinflammatory molecules are transcriptionaly regulated during response. Despite of this,translational regulation is not fully elucidated especially in a comprehensive fashion. In this ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-4288 | biostudies-arrayexpress
TranscriptomicsComparision of expression profile between wild-type and Slc39a13 knockout osteoblasts
In order to explore molecules whose expression is controlled by Slc39a13, we investigated gene expression profiling of primary osteoblast isolated from wild-type and Slc39a13 knockout mice. Keywords: knockout vs wild-type wild-type vs Slc39a13 knockout
ORGANISM(S): Mus musculus 
2008-11-07 | E-GEOD-10555 | biostudies-arrayexpress
UnknownAutomated Quantification of Extranuclear ERα using Phosphor-integrated Dots for Predicting Endocrine Therapy Resistance in HR+/HER2- Breast Cancer.
Not available
S-EPMC6520781 | biostudies-literature
TranscriptomicsEffects of PMA on exon usage of HL60, THP-1, and U937 cells
Myeloid leukemia cell lines HL60, THP-1, and U937 undergo macrophage-like differentiation after treatment with phorbol ester. To explore genes whose exon usage was altered during macrophage differentiation, we compared exome of PMA-treated (differentated) and vehicle-treated (undifferentiated) myelo...
ORGANISM(S): Homo sapiens 
2013-09-25 | E-GEOD-20567 | biostudies-arrayexpress
TranscriptomicsEffects of gene scilencing of USP2 on expression profiles of HL60 cells
So far, we have found PMA induced USP2b isoform in myeloid leukemia cell lines such as HL60, THP-1, and U937. To explore molecular function of USP2 in the cells, we assess expression profiles of HL60-derivatives continuously expressing shRNA for USP2 and control shRNA. HL60 derivatives continuously ...
ORGANISM(S): Homo sapiens 
2013-08-27 | E-GEOD-20476 | biostudies-arrayexpress
TranscriptomicsThe nuclear actin-related protein Arp6 contributes to the radial positioning of chromosome territories.
The chromatin of individual chromosomes is organized into chromosome territories (CTs) in the interphase nucleus. The spatial arrangement of CTs is non-random and evolutionarily conserved. The gene-dense and gene-poor CTs are positioned in the nuclear center and periphery, respectively. As candidate...
ORGANISM(S): Gallus gallus 
2015-11-04 | E-GEOD-14220 | biostudies-arrayexpress
TranscriptomicsEffects of supernatants of USP2 knockdown HL-60 cells and mock transfected HL60 cells on differentiated 3T3-L1 cells
Ubiquitin specifc protease (USP) 2 modulates various cellular responces including carcinogenesis, spermatogenesis, and glucose metabolism. So far, we established USP2 knockdown HL-60 cells to explore roles of USP2 in macrophages. In this experiment, we investigated whether USP2 knockdown HL-60 cells...
ORGANISM(S): Mus musculus 
2013-08-27 | E-GEOD-43313 | biostudies-arrayexpress
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