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UnknownTreatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3.
Not available
S-EPMC5652397 | biostudies-literature
UnknownLymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels.
Not available
S-EPMC5455597 | biostudies-literature
UnknownRandomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Not available
S-EPMC4981979 | biostudies-literature
TranscriptomicsPmel CD8+ stim 1 vs. stim 2
Repeat experiments of CD8+ pmel effector cells following one and two rounds of restimulation
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-2348 | biostudies-arrayexpress
TranscriptomicsMurine CD8+ Pmel Lymphocytes IL-2 vs. IL-15
Central memory tumor-reactive CD8+ T cells confer superior antitumor immunity compared to effector memory T cells
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-2578 | biostudies-arrayexpress
TranscriptomicsCD8+ T-cell memory bears the transcriptional imprint of progressive differentiation
The generation of CD8+ T-cell memory is an important aim of immunization. While several distinct subsets of CD8+ T-cell memory have been described, the lineage relationships between effector (EFF), effector memory (EM) and central memory (CM) T cells remain contentious. Specifically, there is contra...
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-42459 | biostudies-arrayexpress
TranscriptomicsThe transcription factor BACH2 is required to establish immunosuppression within tumors
Through a diversity of functional lineages, cells of the innate and adaptive immune system either drive or constrain immune reactions within tumors. Thus, while the immune system has a powerful ability to recognize and kill cancer cells, this function is often suppressed preventing clearance of dise...
ORGANISM(S): Mus musculus 
2016-06-01 | E-GEOD-74653 | biostudies-arrayexpress
TranscriptomicsT cell oxygen-sensing proteins establish an immunologically tolerant metastatic niche
Cancer cells must evade immune responses at distant sites to establish metastases. The lung is a frequent site for metastasis. We hypothesized that lung-specific immunoregulatory mechanisms create an immunologically permissive environment for tumor colonization. We found that T cell-intrinsic expres...
ORGANISM(S): Mus musculus 
2016-08-03 | E-GEOD-85131 | biostudies-arrayexpress
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