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TranscriptomicsImprovement of Lactobacillus plantarum Aerobic Growth by Comprehensive Transcriptome Analysis
An aerobic Lactobacillus plantarum culture displayed growth stagnation during early growth. Transcriptome analysis revealed that regain of growth after stagnation correlated with activation of CO2-producing pathways suggesting that limiting CO2-concentration induced stagnation. Analogously providing...
ORGANISM(S): Lactobacillus plantarum WCFS1 
2010-05-26 | E-GEOD-10194 | biostudies-arrayexpress
UnknownHigh-throughput identification and validation of in situ-expressed genes of Lactococcus lactis.
Not available
S-EPMC2519351 | biostudies-literature
TranscriptomicsMicrobiota facilitates dietary heme-induced epithelial hyperproliferation and hyperplasia by breaking the mucus barrier
Colorectal cancer risk is associated with diets high in red meat. Heme, the pigment of red meat, induces cytotoxicity of colonic contents and elicits epithelial damage and compensatory hyperproliferation, leading to hyperplasia. Here we explore the possible causal role of the gut microbiota in heme-...
ORGANISM(S): Mus musculus 
2015-08-03 | E-GEOD-40670 | biostudies-arrayexpress
TranscriptomicsComparative analysis of bacterial transcriptome using DNA microarray and next generation sequencing technologies
Validation of Lactobacillus plantarum WCFS1 transcriptome profile using RNA sequencing (direct cDNA sequencing and 3'-UTR sequencing) in comparison with DNA microarray as a reference platform. Transcriptome analysis was performed on total RNA and enriched mRNA of L. plantarum WCFS1 grown in CDM or M...
ORGANISM(S): Lactobacillus plantarum 
2012-07-09 | E-GEOD-35754 | biostudies-arrayexpress
UnknownStool energy density is positively correlated to intestinal transit time and related to microbial enterotypes.
Not available
S-EPMC9743556 | biostudies-literature
TranscriptomicsIdentification of the core gene-regulatory network that governs the dynamic adaptation of intestinal homeostasis during conventionalization in mice
Molecular adaptation of the intestinal mucosa occurs during microbial conventionalization to maintain a balanced immune response. However, the genetic regulation of such adaptation is obscure. Here, combined analysis of germ free and conventionalized mice revealed that the major molecular adaptation...
ORGANISM(S): Mus musculus 
2012-07-10 | E-GEOD-32513 | biostudies-arrayexpress
ModelsHoefnagel2002_PyruvateBranches
This a model from the article: Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis. Hoefnagel MH, Starrenburg MJ, Martens DE, Hugenholtz J, Kleerebezem M, Van Swam II, Bongers R, Westerh...
2024-09-02 | BIOMD0000000017 | BioModels
UnknownAssessing the Impact of Diet on the Mucosa-Adhered Microbiome in Piglets Using Comparative Analysis of Rectal Swabs and Colon Content.
Not available
S-EPMC8902596 | biostudies-literature
TranscriptomicsSaturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine
We studied the effect of dietary fat type, varying in polyunsaturated/saturated fatty acid ratio's (P/S) on development of metabolic syndrome. C57Bl/6J mice were fed purified high-fat diets (45E% fat) containing palm oil (HF-PO; P/S 0.4), olive oil (HF-OO; P/S 1.1) or safflower oil (HF-SO; P/S 7.8) ...
ORGANISM(S): Mus musculus 
2012-06-17 | E-GEOD-18586 | biostudies-arrayexpress
TranscriptomicsPeroxide stress in Sigma54 mutant and Wt
Analyses of the Wild type and the sigma 54 mutant strain NZ7306 with and without peroxide treatment: A Lactobacillus plantarum strain with a deletion in the alternative sigma factor 54 (?54) encoding gene rpoN, displayed a 100 fold higher sensitivity to peroxide as compared to its parental strain. T...
ORGANISM(S): Lactobacillus plantarum 
2008-05-08 | E-GEOD-11351 | biostudies-arrayexpress
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