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TranscriptomicsTranscription profiling of mouse WAP-SVT/t transgenic animals during breast cancer formation
Microarray studies revealed that as a first hit, SV40 T/t-antigen causes deregulation of 462 genes in mammary gland cells (ME-cells) of WAP-SVT/t transgenic animals. The majority of deregulated genes are cell-proliferation specific and Rb-E2F dependent, causing ME-cell proliferation and gland hyperp...
ORGANISM(S): Mus musculus 
2009-04-25 | E-GEOD-6246 | biostudies-arrayexpress
MetabolomicsEvaluation of sample preparation methods for NMR-based metabolomics of cow milk
The quality of milk metabolome analyzed by nuclear magnetic resonance (NMR) is greatly influenced by the way samples are prepared. Although this analytical method is increasingly used to study milk metabolites, a thorough examination of available sample preparation protocols for milk has not been re...
2019-06-13 | MTBLS623 | MetaboLights
TranscriptomicsTranscription profiling of human and mouse breast cancers
This SuperSeries is composed of the following subset Series:; GSE6581: Expression data from mammary glands of transgenic mice; GSE6596: Comparison of gene expression data from human and mouse breast cancers: Identification of conserved breast tumor genes Experiment Overall Design: Refer to individua...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6772 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human colorectal cancer cell lines treated with O-glycan inhibitors generate aryl-glycans, induce apoptosis, and inhibit growth
Our studies provide direct evidence that O-glycosylation pathways play a role in the regulation of cell growth through apoptosis and proliferation pathways. Eight small molecular weight analogues of the GalNAc-alpha-1-O-serine/threonine structure based on 1-benzyl-2-acetamido-2- deoxy-alpha-O-D-gala...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-12422 | biostudies-arrayexpress
ProteomicsComparative Proteome Analysis in Schizosaccharomyces pombe identifies metabolic targets to improve protein production and secretion
This dataset contains additional experimental results for the determination of the effect of Fluconazole and amino acid supplementation to the NW10 strain of S. pombe. Protein secretion in yeast is a complex process and its efficiency depends on a variety of parameters. We performed a comparative p...
ORGANISM(S): Schizosaccharomyces pombe 
2016-08-08 | PXD003016 | Pride
Isobaric labeling 2d-lc maldi ms 5800 proteome analyzer High/low ph lc Itraq 
ProteomicsComparative Proteome Analysis in Schizosaccharomyces pombe identifies metabolic targets to improve protein production and secretion
Protein secretion in yeast is a complex process and its efficiency depends on a variety of parameters. We performed a comparative proteome analysis of a set of Schizosaccharomyces pombe strains producing the alpha-glucosidase maltase in increasing amounts to investigate the overall proteomic respons...
ORGANISM(S): Schizosaccharomyces pombe 
2016-08-08 | PXD002693 | Pride
Isobaric labeling 2d-lc maldi ms 5800 proteome analyzer High/low ph lc Itraq 
TranscriptomicsInfluence of alkyl-phospholipids on the gene expression profile of immortalized keratinocytes HaCaT
New alkyl-phospholipids (APLs) that are structurally derived from the platelet-activating factor are promising candidates for anticancer treatment. After the incorporation into cell membranes, APLs are able to interfere with a wide variety of key enzymes implicated in cell growth, motility, invasion...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-20722 | biostudies-arrayexpress
UnknownAddictive Potential of e-Cigarettes as Reported in e-Cigarette Online Forums: Netnographic Analysis of Subjective Experiences.
Not available
S-EPMC9862333 | biostudies-literature
TranscriptomicsTranscription profiling of human large cell anaplastic lymphoma and classical Hodgkin lymphoma
Analysis of differential gene expression in human non-Hodgkin`s lymphoma cell lines and a primary leukaemic tumor sample of large cell anaplastic type in comparison with Hodgkin`s lymphoma cell lines and other non-Hodgkin`s lymphoma samples and non-neoplastic lymphocytes Experiment Overall Design: S...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4109 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression data from human and mouse breast cancers: Identification of conserved breast tumor genes
The aim of our work was the comparison of human and mouse gene expression data and to identify a conserved breast tumor gene set. The results encourage the usefulness of transgenic mice as a model for human breast cancer formation and therapy. Keywords: Comparison of gene expression data The aim of ...
ORGANISM(S): Homo sapiens 
2007-01-12 | E-GEOD-6596 | biostudies-arrayexpress
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