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ProteomicsHAX1 controls mitochondrial proteostasis
The relevance of mitochondrial proteostasis for the differentiation and function of hematopoietic and immune cells is unknown. Dissecting the HCLS1-associated protein X-1 (HAX1) –related protein network, we define a functional CLPB-HAX1-PRKD2-HSP27 axis with critical importance for the differentiati...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD023790 | Pride
Inborn errors of immunity Severe congenital neutropenia Protein quality control Hematopoiesis 
TranscriptomicsTranscription profiling of mouse breast cancer laser microdissected samples to assess the expression of invasion-associated proteases in atypical ductal hyperplasia at week 9 and large carcinomas at week 27
CDNA array analysis of laser microdissected samples to assess the expression of invasion-associated proteases in ADH at week 9 and large carcinomas at weekt 27.
ORGANISM(S): Mus musculus 
2008-01-21 | E-MEXP-1381 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for breast cancer formation in mouse
We investigated the CNAs in a four stage tumorigenesis model. This model included copy number analyses in non-transgenic NMRI mice (normal) and in transgenic SVT/t mice: non-malignant hyperplastic mammary glands and breast cancers, as well as breast cancer derived cell lines. We focused our research...
ORGANISM(S): Mus musculus 
2012-09-04 | E-GEOD-35873 | biostudies-arrayexpress
TranscriptomicsExpression data from human peripheral blood lymphocytes stimulated with anti-CD3 and anti-CD28 antibodies.
Peripheral blood lymphocytes were separated in the Ficoll gradient and subjected for stimulation with anti-CD3 and anti-CD28 antiobodies upon time (6h, 12h and 18h). Next, total RNA was isolated and trenscriptional analysis of stimulated cells was performed. 11 total samples were analysed. Analysis ...
ORGANISM(S): Homo sapiens 
2013-02-25 | E-GEOD-29624 | biostudies-arrayexpress
TranscriptomicsTranscriptome partitioning in mouse fertilization.
RNA transcripts are distributed non-uniformly in the oocytes of many animals, such that newly-divided embryo cells (blastomeres) inherit distinct transcriptomes following fertilization. In animals such as the frog, Xenopus laevis, programmed transcript regionalization directs early embryonic axis fo...
ORGANISM(S): Mus musculus 
2011-04-21 | E-GEOD-27396 | biostudies-arrayexpress
UnknownAssociations Among in-The-Moment Emotional Clarity, Emotion Regulation, and Psychopathology in Obsessive-Compulsive Disorder.
Not available
S-EPMC12638152 | biostudies-literature
TranscriptomicsTranscription profiling of early dendritic cell DC development in hematopoietic progenitor cell line FDCP-mix that is permissive for DC differentiation in the presence of GMCSF
To identify transcription factors that control dendritic cell development, we performed transcriptional profiling analyses of the murine hematopoietic progenitor cell line FDCP-mix that is permissive for DC differentiation in the presence of GMCSF.We reasoned that GM-CSF modulates a defined set of d...
ORGANISM(S): Mus musculus 
2004-08-18 | E-MEXP-151 | biostudies-arrayexpress
TranscriptomicsMicroarray correpsonding to the paper manuscript titled: Targeted expression profiling of single disseminated cancer cells isolated from bone marrow of prostate cancer patients
Bone is the most frequent site of metastasis in prostate cancer (PCa) and patients with bone metastases are deemed incurable. Targeting prostate cancer cells that disseminated to the bone marrow (BM) prior to surgery and before metastatic outgrowth may therefore prevent lethal metastasis. This promp...
ORGANISM(S): Homo sapiens 
2014-10-20 | E-GEOD-59631 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human large cell anaplastic lymphoma and classical Hodgkin lymphoma
Analysis of differential gene expression in human non-Hodgkin`s lymphoma cell lines and a primary leukaemic tumor sample of large cell anaplastic type in comparison with Hodgkin`s lymphoma cell lines and other non-Hodgkin`s lymphoma samples and non-neoplastic lymphocytes Experiment Overall Design: S...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4109 | biostudies-arrayexpress
TranscriptomicsProfiling of single murine bronchioalveolar stem cells
Murine bronchioalveolar stem cells play a key role in pulmonary epithelial maintenance and repair but their molecular profile is poorly described so far. In this study, we used antibodies directed against Sca-1 and CD34, two markers originally ascribed to pulmonary cells harboring regenerative poten...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-52215 | biostudies-arrayexpress
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