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UnknownHepatic decompensation in antiretroviral-treated patients co-infected with HIV and hepatitis C virus compared with hepatitis C virus-monoinfected patients: a cohort study.
Not available
S-EPMC4254786 | biostudies-literature
TranscriptomicsWhole transcriptome profiling of the rat pineal gland during development from embryonic day 21 to adult
The transcriptome of the rat pineal gland is highly dynamic, with many hundreds of genes changing more than two-fold on a 24-hr daily rhythm, as revealed earlier using Affymetrix GeneChip analysis. Several key transcription factors and enzymes are known to change dramatically during development of t...
ORGANISM(S): Rattus norvegicus 
2014-10-24 | E-GEOD-46127 | biostudies-arrayexpress
UnknownDe novo loss-of-function variants in STAG2 are associated with developmental delay, microcephaly, and congenital anomalies.
Not available
S-EPMC7033032 | biostudies-literature
TranscriptomicsTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
The cone-rod homeobox gene (Crx) encodes Crx, a transcription factor selectively expressed in two cell types, retinal photoreceptors and the melatonin secreting pinealocytes of the pineal gland. In this report the role of Crx in regulating gene expression in the mammalian pineal gland was extended u...
ORGANISM(S): Mus musculus 
2012-01-01 | E-GEOD-24625 | biostudies-arrayexpress
TranscriptomicsSelective knockout of NeuroD1 in the retina and pineal gland
NeuroD1 encodes a basic helix-loop-helix transcription factor involved in the development of neural and endocrine structures. NeuroD1 mRNA is highly abundant in the adult mammalian pineal gland and exhibits a developmental expression pattern similar to the retina. This is consistent with the common ...
ORGANISM(S): Mus musculus 
2012-07-25 | E-GEOD-35396 | biostudies-arrayexpress
TranscriptomicsWhole transcriptome profiling of rat pineal glands and retinas collected throughout a 24-hour cycle
The rat pineal transcriptome is highly dynamic, with many hundreds of transcripts changing more than two-fold on a 24-hr basis, as revealed earlier using Affymetrix GeneChip analysis. The retina is evolutionally related to the pineal gland so these two tissues share many gene expression patterns. Th...
ORGANISM(S): Rattus norvegicus 
2014-02-05 | E-GEOD-46069 | biostudies-arrayexpress
GenomicsEGAS00001000515-sc-20141203 - samples
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAD00001001090 | EGA
GenomicsEGAS00001000603-sc-20140423 - samples
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAD00001000825 | EGA
GenomicsUse of Deep Sequencing to Dectect Clonal Mutations In Sun Exposed Skin Epidermis PART2
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAS00001000603 | EGA
GenomicsUse of Deep Sequencing to Dectect Clonal Mutations In Sun Exposed Skin Epidermis
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tiss...
EGAS00001000515 | EGA
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