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ProteomicsAggregation-state–resolved analysis of the tau interactome in Alzheimer’s disease
This project investigates how tau-associated protein networks are remodelled in Alzheimer’s disease and how these changes relate to the progression of tau aggregation in the human brain. Using post-mortem brain tissue from individuals with Alzheimer’s disease and age-matched healthy controls, the st...
ORGANISM(S): Homo sapiens (Human) 
2026-09-28 | PXD072117 | Pride
Human Brain Tau aggregates Interactome 
ProteomicsHuman tau 0N4R isoform hyperphosphorylation LC-MS/MS
Soluble aggregates of the microtubule-associated protein tau have been challenging to assemble and characterize, despite their important role in the development of tauopathies. We found that sequential hyperphosphorylation by protein kinase A in conjugation with either glycogen synthase kinase 3beta...
ORGANISM(S): Homo sapiens (Human) 
2022-04-13 | PXD033127 | Pride
Hyperphosphorylation Tau Human Lc-ms/ms 
ProteomicsProtein-agnostic pulldown of brain-derived aggregates from Motor Neuron Disease
Characterisation of homognised BA tissue extracts from TDP-43 MND (×5), SOD1-MND (×2) and neurologically normal controls (×3) using the protein-agnostic aggregate probe CAP1.
ORGANISM(S): Homo sapiens (Human) 
2026-02-03 | PXD061429 | Pride
Human Aggregate Als Mnd 
UnknownExtrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution.
Not available
S-EPMC6127805 | biostudies-literature
TranscriptomicsExpression data from human cord blood CD161++/CD161+/CD161- CD8+ T cell subsets
We used microarray to compare gene expression between CD161++/CD161+/CD161-CD8+ T cells from human cord blood. Lymphocytes from freshly obtained human cord blood samples were isolated by Ficoll density centrifugation. CD8+ T cells were purified by negative selection using magnetic beads and subseque...
ORGANISM(S): Homo sapiens 
2012-01-25 | E-GEOD-33424 | biostudies-arrayexpress
UnknownImmune-epithelial-stromal networks define the cellular ecosystem of the small intestine in celiac disease.
Not available
S-EPMC12133578 | biostudies-literature
UnknownResidual lung abnormality following COVID-19 hospitalisation is characterised by biomarkers of epithelial injury.
Not available
S-EPMC12860639 | biostudies-literature
UnknownGuidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Not available
S-EPMC7350392 | biostudies-literature
UnknownPhysical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Not available
S-EPMC8497028 | biostudies-literature
UnknownPara-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Not available
S-EPMC10746705 | biostudies-literature
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