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ProteomicsProteomic characterization and label-free comparison of outer membrane vesicles from Francisella tularensis subsp. holarctica strain FSC200 isolated from different cultivation conditions
Francisella tularensis is a Gram-negative, facultative intracellular bacterium, causing a severe disease known as tularemia. It is known to secrete unusually shaped nanotubular outer membrane vesicles (OMV) loaded with number of virulence factors and immunoreactive proteins. In this study the nanotu...
ORGANISM(S): Francisella tularensis subsp. holarctica Francisella tularensis subsp. holarctica FSC200 
2019-09-30 | PXD013074 | Pride
Francisella tularensis  fsc200  outer membrane vesicles  stress response 
ProteomicsCross-species proteomic comparison of whole cell lysates, outer membrane vesicles and membrane fractions of Francisella tularensis subsp. tularensis versus subsp. holarctica
Secretion of outer membrane vesicles (OMV) presents an important phenomenon in Gram-negative bacteria and they play multiple roles in their lifestyle including virulence and host-pathogen interaction. Francisella tularensis secretes unusually shaped tubular OMV. We here present a proteomic compariso...
ORGANISM(S): Francisella tularensis Francisella tularensis subsp. tularensis SCHU S4 Francisella tularensis subsp. holarctica FSC200 
2021-02-08 | PXD022406 | Pride
Q-exactive Schus4 Outer membrane vesicles Fsc200 Cross-species proteomic comparison Francisella tularensis 
ProteomicsProtein profiling of plasma samples of patients with dilated cardiomyopathy and differences according to the disease prognosis
Dilated cardiomyopathy (DCM) is a disease of the heart muscle characterized by left ventricular or biventricular dilation and systolic dysfunction. It presents one of the most common causes of heart failure worldwide and also the most common indication for heart transplantation. Despite the discharg...
ORGANISM(S): Homo sapiens (Human) 
2024-02-19 | PXD046288 | Pride
Left ventricular reverse remodeling Lfq Functional enrichment analysis Plasma proteome profiling Dilated cardiomyopathy Lc-ms/ms 
ProteomicsFrancisella tularensis DsbA mutant MS/SILAC analysis
Comparison of enriched membrane fractions of Francisella tularensis subsp. holarctica strain FSC200 and its DsbA mutant by SILAC analysis.
ORGANISM(S): Francisella tularensis subsp. holarctica FSC200 
2018-01-15 | PXD007682 | Pride
Q-exactive Silac Francisella tularensis 
ProteomicsQuantitative proteomic study of two cervical cancer cell lines upon re-expression of Galectin 7
Galectin-7 expression was found to be strongly reduced in cervical cancer cell lines. The same tumor cell lines in which Galectin-7 was ectopically expressed exhibited significant decrease in their tumorigenic capacity in vitro and in vivo. The proteomic changes in the cervical cancer cell lines HeL...
ORGANISM(S): Homo sapiens (Human) 
2016-09-28 | PXD001806 | Pride
Cervical cancer Q-exactive Siha Galectin-7 Hela Silac 
ProteomicsImpact of HPV16 E6 and E7 oncogenes together with Chlamydia trachomatis infection on proteome changes in immortalized oral keratinocytes
Certain types of Human papilloma viruses (HPV) are the etiological agents for cervical cancer. However, not all infections of high-risk HPVs will finally lead to cancer since most HPV infections are cleared without any consequences. Chlamydia trachomatis is the most prevalent sexual transmitted bact...
ORGANISM(S): Human papillomavirus type 16 Chlamydia trachomatis Homo sapiens (Human) 
2019-03-18 | PXD012186 | Pride
Cervical cancer Human papillomavirus Chlamydia trachomatis 
ProteomicsQuantitative proteomic study of two cervical cancer cell lines upon re-expression of Galectin 7
Galectin-7 expression was found to be strongly reduced in cervical cancer cell lines. The same tumor cell lines in which Galectin-7 was ectopically expressed exhibited significant decrease in their tumorigenic capacity in vitro and in vivo. The proteomic changes in the cervical cancer cell lines HeL...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080855 | MassIVE
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