Sort   by:  
 Page size 
ProteomicsReconstitution of 3’-processing of mammalian pre-mRNA reveals a central role of RBBP6
The 3’ ends of almost all eukaryotic mRNAs are generated in an essential two-step processing reaction, endonucleolytic cleavage of an extended precursor followed by the addition of a poly(A) tail. By reconstituting the reaction from overproduced and purified proteins, we provide a minimal list of fo...
ORGANISM(S): Homo sapiens (Human) 
2022-03-04 | PXD031227 | Pride
Cpsf 3’-processing Xl-ms Rbbp6 
TranscriptomicsLPS response of cardiovascular endothelial cells transduced with an APEX1(1-20) expressing vector or an empty vector
Sepsis is an exaggerated immune response upon infection with lipopolysaccharide (LPS) as the main causative agent. LPS-induced activation and apoptosis of endothelial cells (EC) can lead to organ dysfunction and finally organ failure. We have previously demonstrated that the first twenty amino acid...
ORGANISM(S): Homo sapiens 
2021-09-20 | E-MTAB-10936 | biostudies-arrayexpress
Sort   by:  
 Page size