Sort   by:  
 Page size 
ProteomicsCMK LC-MS/MS after CoIP of ARID3A
In order to determine proteins interacting with ARID3A in the ML-DS cell line CMK, we performed CoIP of endogenous ARID3A followed by LC-MS/MS
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD025027 | Pride
Cmk Arid3a Ml-ds 
TranscriptomicsGATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia
Transient leukemia (TL) is evident in 5-10% of all neonates with Down syndrome (DS) and associated with N-terminal truncating GATA1-mutations (GATA1s). Here we analyzed the effect of on gene expression upon ectopic expression of Gata1s or Gata1, while simultaneously knocking down endogenous GATA1,...
ORGANISM(S): Homo sapiens 
2014-03-28 | E-GEOD-56332 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of Down Syndrome (DS)-AMKL and non-DS AMKL samples
The goal of this study is to define a gene expression signature unique to DS-AMKL (acute megakaryoblastic leukemia or FAB M7 leukemia). A similar study was done previously, but using unfractionated patient leukemic samples. In this study, we sorted megakaryocytic leukemia blasts from patients and th...
ORGANISM(S): Homo sapiens 
2010-08-01 | E-GEOD-16677 | biostudies-arrayexpress
ProteomicsRUNX1 isoforms in leukemogenesis
Aneuploidy and structural aberrations affecting chromosome 21 (Hsa21) are the most frequent in cytogentic events in acute myeloid leukemia. However, it remains unclear why leukemic blasts select for amplifications of Hsa21 or parts of it and why children with Down syndrome (i.e. trisomy 21) are at a...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD030616 | Pride
Down syndrome Runx1 Acute myeloid leukemia Gata1 Transient abnormal myelopoiesis 
Sort   by:  
 Page size