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TranscriptomicsAberrant BAF57 Signaling Facilitates Pro-metastatic Phenotypes
BAF57, a component of the SWI/SNF chromatin remodeling complex conglomerate,modulates androgen receptor activity to promote prostate cancer. However the molecular consequences of tumor associated BAF57 elevation have remianed undefined in advanced disease such as castration resistant prostate cance...
ORGANISM(S): Homo sapiens 
2013-06-04 | E-GEOD-44418 | biostudies-arrayexpress
TranscriptomicsGene expression data from treated LNCaP prostate cells.
Prostate cancer is dependent on androgen receptor (AR) signaling at all stages of the disease and cyclin D1 has been shown to negatively modulate the expression of the AR-dependent gene prostate specific antigen (KLK3/PSA). Unbiased gene expression profiling was performed to determine the androgen-r...
ORGANISM(S): Homo sapiens 
2011-01-07 | E-GEOD-26483 | biostudies-arrayexpress
TranscriptomicsApplication of a clinical assay for staging and prognosis of prostate cancer diagnosed in needle core biopsy specimens
Molecular and genomic analysis of microscopic quantities of tumor from formalin-fixed and paraffin-embedded (FFPE) biopsies has many unique challenges. Here we evaluated the feasibility of obtaining transcriptome-wide RNA expression to measure prognostic classifiers from diagnostic prostate needle c...
ORGANISM(S): Homo sapiens 
2016-03-09 | E-GEOD-72220 | biostudies-arrayexpress
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