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MetabolomicsInositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites
Vesicular traffic and membrane contact sites between organelles enable the exchange of proteins, lipids, and metabolites. Recruitment of membrane tethers to contact sites between the endoplasmic reticulum (ER) and the plasma membrane is often triggered by calcium. In contrast, we reveal here a funct...
2021-05-06 | MTBLS2444 | MetaboLights
ProteomicsProtein aggregation is a consequence of the dormancy-inducing membrane toxin TisB in Escherichia coli
Protein aggregates occur in all living cells due to misfolding of proteins. In bacteria, protein aggregation is associated with cellular inactivity, which is related to dormancy and tolerance to stressful conditions, including the exposure to antibiotics. In Escherichia coli, the membrane toxin TisB...
ORGANISM(S): Escherichia coli 
2024-10-04 | PXD049478 | Pride
Toxin-antitoxin system Antibiotics Dormancy Protein aggregation Type i toxin 
TranscriptomicsAutotaxin is expressed in FLT3-ITD positive acute myeloid leukemia and hematopoietic stem cells and promotes cell migration and proliferation
Autotaxin (ATX) has been reported to act as a motility and growth factor in a variety of cancer cells. The ATX protein acts as a secreted lysophospholipase D (lysoPLD) by converting lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA), which signals via G-protein coupled receptors and has im...
ORGANISM(S): Homo sapiens 
2013-05-10 | E-MTAB-1169 | biostudies-arrayexpress
UnknownObese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition.
Not available
S-EPMC7720933 | biostudies-literature
UnknownLineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics.
Not available
S-EPMC6408267 | biostudies-literature
UnknownMetabolic modeling of single Th17 cells reveals regulators of autoimmunity.
Not available
S-EPMC8621950 | biostudies-literature
UnknownAn IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets.
Not available
S-EPMC7771052 | biostudies-literature
UnknownTargeting IL6-Edn1-FoxO1 axis enables lung growth in mechanically ventilated newborn mice.
Not available
S-EPMC12675960 | biostudies-literature
ProteomicsM.musculus - Whole organism, Empai (Menschaert,mcp,2013)
abundance based on MAPPED_BY_AUTHORS, emPAI, Interaction consistency score: 3.6, Coverage: 13
ORGANISM(S): 10090 
2013-00-00 | 61138479 | PAXDB
ProteomicsM.musculus - Whole organism, Nsaf (Menschaert,mcp,2013)
abundance based on MAPPED_BY_AUTHORS, NSAF, Interaction consistency score: 5.2, Coverage: 13
ORGANISM(S): 10090 
2013-00-00 | 2944066562 | PAXDB
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