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TranscriptomicsRNA-Seq of human bronchoalveolar lavage and lung biopsy samples in the segmental endotoxin challenge model
Segmental instillation of lipopolysaccharide (LPS) by bronchoscopy can be used as a model to safely induce transient airway inflammation in the human lung. The LPS challenge model enables investigation of cellular mechanisms involved in pulmonary inflammatory processes as well as pharmacodynamic ana...
ORGANISM(S): Homo sapiens 
2024-03-01 | E-MTAB-13318 | biostudies-arrayexpress
ProteomicsDietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse
Suitable animal models are essential for translational research, especially in the case of complex, multifactorial conditions, such as obesity. The non-inbred mouse (Mus musculus) line Titan, also known as DU6, is one of the world’s longest selection experiments for high body mass and was previously...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-04 | PXD019030 | Pride
Acetylome Shotgun proteomics Titan mouse model Metabolic syndrome 
UnknownGPC3-mediated metabolic rewiring of diabetic mesenchymal stromal cells enhances their cardioprotective functions via PKM2 activation.
Not available
S-EPMC11490746 | biostudies-literature
GenomicsGenomic mapping of cAMP receptor protein binding in relation to transcriptional start sites in Mycobacterium tuberculosis
In this study we have used ChIPseq analysis to perform comprehensive mapping of the binding profile of the cAMP receptor protein (CRPMt) of M. tuberculosis combined with RNAseq studies to further investigate the transcriptional response following crp gene deletion and under alternative growth condi...
ORGANISM(S): Mycobacterium tuberculosis 
2014-06-24 | E-MTAB-2390 | biostudies-arrayexpress
ProteomicsMtb_Trypsin_Lysc
The digestive enzymes are trypsin and Lysc
ORGANISM(S): Mycobacterium Tuberculosis 
2012-12-31 | PAe003638 | PeptideAtlas
ProteomicsMtb_Trypsin_Lysc_membrane
The digestive enzymes are trypsin and Lysc, membrane
ORGANISM(S): Mycobacterium Tuberculosis 
2012-12-31 | PAe003637 | PeptideAtlas
ProteomicsMtb_Triple_Digest
The digestive enzymes are trypsin, chymotrypsin and Lysc
ORGANISM(S): Mycobacterium Tuberculosis 
2012-12-31 | PAe003636 | PeptideAtlas
ProteomicsMtb_Triple_Digest_membrane
The digestive enzymes are trypsin, chymotrypsin and Lysc, membrane
ORGANISM(S): Mycobacterium Tuberculosis 
2012-12-31 | PAe003635 | PeptideAtlas
TranscriptomicsNID2 and HOXA9 promoter hypermethylation as biomarkers to prevent and detect Oral Cavity Squamous Cell Carcinoma
Differentially methylated oral squamous cell carcinoma (OSCC) biomarkers, identified in-vitro and validated in well-characterized surgical specimens, have shown poor clinical correlation in cohorts with different risk profiles. To overcome this lack of relevance we used the HumanMethylation27 BeadCh...
ORGANISM(S): Homo sapiens 
2013-02-13 | E-GEOD-28217 | biostudies-arrayexpress
TranscriptomicsMycobacterium smegmatis: CarD depletion (mgm1703) vs Control (mgm1701)
Transcriptional profiling of Mycobacterium smegmatis comparing the effects of wild type levels of CarD expression with CarD depletion. Transcriptional profile of the mgm1701 control strain was compared with that of mgm1703, a strain where CarD transcription is regulated by a Tet-On system. Both stra...
ORGANISM(S): Mycobacterium smegmatis 
2010-05-16 | E-GEOD-15437 | biostudies-arrayexpress
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