Koch Michael M - OmicsDI

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Unknown (70)
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biostudies-arrayexpress (28)
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Mass Spectrometry (15)
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Transcription profiling by array (15)
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Lab affiliation

Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA (4)
Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA (2)
Department of Biological Engineering Massachusetts Institute of Technology Cambridge MA 02139, Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology Cambridge MA 02142 USA, Center for Precision Cancer Medicine Massachusetts Institute of Technnology Cambridge MA 02142 USA (1)
Department of Immunology, Interfaculty Institute for Cell Biology, Tübingen, Germany (1)
Department of Molecular Mechanisms of Disease, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland (1)
Department of Molecular Mechanisms of Disease, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland (1)
Department of Neurology, Faculty of Medicine, University of Cologne and University Hospital Cologne, Kerpener Strasse 62, 50937 Cologne, Germany (1)
IMP - Research Institute of Molecular Pathology, Austria (1)
IMP - Research Institute of Molecular Pathology, Vienna, Austria (1)
University of Cologne Faculty of Medicine and Cologne University Hospital Department I of Internal Medicine Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf Center for Molecular Medicine Cologne CECAD Center of Excellence on Cellular Stress Responsesin Aging-Associated Diseases 50931 Cologne Germany (1)
University of Cologne, Faculty of Medicine and Cologne University Hospital, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Center for Molecular Medicine Cologne; CECAD Center of Excellence on Cellular Stress Responses in Aging-Associated Diseases, 50931 Cologne, Germany (1)

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THOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 induced macrophage differentiation

THOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 induced macrophage differentiation, thereby playing a key role in the mRNA export of immediate early genes induced by CSF-1 stimulation. Hematopoiesis, growth, differentiation, and commitment...

ORGANISM(S): Mus musculus

2013-12-24 | E-GEOD-41170 | biostudies-arrayexpress

Role of M. tuberculosis in CO sensing

This SuperSeries is composed of the following subset Series: GSE11095: Dose response of carbon monoxide treatment of M. tuberculosis GSE11096: Role of M. tuberculosis dosS and dosT in CO sensing Refer to individual Series

ORGANISM(S): Mycobacterium tuberculosis

2008-05-28 | E-GEOD-10897 | biostudies-arrayexpress

Transcriptional profile comparison of M. tuberculosis PDIM spontaneous mutants

Transcriptional profile comparison among PDIM positive and negative isolates. Standard in vitro exponential phase cultures of M. tuberculosis H37Rv ATCC27294 were plated on 7H11 plates. Individual colonies were sub-cultured in 7H9 broth and metabolically labeled with [14C] propionic acid. The apolar...

ORGANISM(S): Mycobacterium tuberculosis

2010-05-16 | E-GEOD-17234 | biostudies-arrayexpress

Synthesis of bicyclic guanidines via cascade hydroamination/Michael additions of mono-N-acryloylpropargylguanidines.

Not available

S-EPMC4260634 | biostudies-literature

Genomic comparison of M. tuberculosis PDIM spontaneous mutants

Genomic comparisons among PDIM positive and negative isolates. Standard in vitro exponential phase cultures of M. tuberculosis H37Rv ATCC27294 were plated on 7H11 plates. Individual colonies were sub-cultured in 7H9 broth and metabolically labeled with [14C] propionic acid. The apolar lipid fraction...

ORGANISM(S): Mycobacterium tuberculosis

2010-05-16 | E-GEOD-17232 | biostudies-arrayexpress

Role of M. tuberculosis dosS and dosT in CO sensing

Transcriptional profiling of M. tuberculosis dosR and dosS mutants and wild type growing in log phase treated with carbon monoxide or nitric oxide versus untreated controls Keywords: Genetic modification Two condition experiment, DETANO treated cells at 100 uM or CO treated cells at 20000 ppm versus...

ORGANISM(S): Mycobacterium tuberculosis

2008-05-28 | E-GEOD-11096 | biostudies-arrayexpress

Dose response of carbon monoxide treatment of M. tuberculosis

Transcriptional profiling of M. tuberculosis growing in log phase treated with various concentrations of carbon monoxide versus untreated controls Keywords: Dose response Two condition experiment, CO treated cells at 2000, 200 and 20 ppm versus untreated controls. Biological replicates: 2 replicates...

ORGANISM(S): Mycobacterium tuberculosis

2008-05-29 | E-GEOD-11095 | biostudies-arrayexpress

Map transformed DNA into W6G from VCXB21

Vibrio cholerae isolate W6G transformed with DNA from VCXB21 and selected for chitosan metabolism. Nine independent transformants compared to parental W6G on microarrays containing probes for all N16961 ORFs. Regions acquired from VCXB21 hybridize more strongly to the array. A genotyping experimen...

ORGANISM(S): Vibrio cholerae

2007-08-16 | E-GEOD-8791 | biostudies-arrayexpress

DNA binding factors shape the mouse methylome at distal regulatory regions [ChIP-seq].

To gain insights into the interplay between DNA methylation and gene regulation we generated a basepair resolution reference map of the mouse methylome in stem cells and neurons. High genome coverage allowed for a novel quantitative analysis of local methylation states, which identified Low Methylat...

ORGANISM(S): Mus musculus

2011-12-09 | E-GEOD-30203 | biostudies-arrayexpress

Transcriptional profiling using microarrays to elucidate the effects of partial whiB1 gene deletion in Mycobacterium tuberculosis H37Rv

DNA microarray analysis was performed on RNA from a strain of Mycobacterium tuberculosis H37Rv in which the essential whiB1 gene was deleted from the chromosome but partially complemented by a wild type allele on a plasmid, compared to RNA from H37Rv wild type containing the same plasmid.

ORGANISM(S): Mycobacterium tuberculosis

2017-12-22 | E-MTAB-5814 | biostudies-arrayexpress

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