Sort   by:  
 Page size 
ProteomicsYield and immunomodulatory effects of pneumococcal membrane vesicles change with bacterial growth phase
We investigated whether isolation of MVs during either the stationary-phase (24 h) or death-phase (48 h) affected their yield, immunogenicity and cytotoxicity in primary human immune cells. Death-phase vesicles showed higher yield than stationary-phase vesicles. Both vesicle types displayed excellen...
ORGANISM(S): Streptococcus pneumoniae (strain ATCC BAA-255 / R6) 
2022-02-16 | PXD026462 | Pride
Proteomics Primary macrophages Death-phase Stationary-phase Bacterial membrane vesicles Vaccine Immunogenicity 
UnknownIn vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection.
Not available
S-EPMC3071295 | biostudies-literature
UnknownPrioritization of pig farm biosecurity for control of Salmonella and hepatitis E virus infections: results of a European expert opinion elicitation.
Not available
S-EPMC9987137 | biostudies-literature
ProteomicsTarget Landscape of Clinical Kinase Inhibitors
Here, we provide a comprehensive overview of the selectivity profiles of 242 kinase inhibitors currently in clinical trials. We screened available inhibitors against human protein kinases by using the Kinobead technology resulting in a drug matrix identifying the druggable kinome and related protein...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-12 | MSV000081932 | MassIVE
TranscriptomicsRNA-Seq of human bronchoalveolar lavage and lung biopsy samples in the segmental endotoxin challenge model
Segmental instillation of lipopolysaccharide (LPS) by bronchoscopy can be used as a model to safely induce transient airway inflammation in the human lung. The LPS challenge model enables investigation of cellular mechanisms involved in pulmonary inflammatory processes as well as pharmacodynamic ana...
ORGANISM(S): Homo sapiens 
2024-03-01 | E-MTAB-13318 | biostudies-arrayexpress
TranscriptomicsPluripotent Stem Cells Escape From Senescence-Associated DNA Methylation Changes [Illumina]
Pluripotent stem cells evade replicative senescence, whereas other primary cells lose their proliferation and differentiation potential after a limited number of cell divisions M-bM-^@M-^S and this is accompanied by specific senescence-associated DNA methylation (SA-DNAm) changes. Here, we investiga...
ORGANISM(S): Homo sapiens 
2012-09-24 | E-GEOD-37066 | biostudies-arrayexpress
TranscriptomicsPluripotent Stem Cells Escape From Senescence-Associated DNA Methylation Changes
This SuperSeries is composed of the following subset Series: GSE37065: Long-term culture associated gene expression changes in MSC [Affymetrix] GSE37066: Pluripotent Stem Cells Escape From Senescence-Associated DNA Methylation Changes [Illumina] GSE38806: Gene expression profiles of induced pluripot...
ORGANISM(S): Homo sapiens 
2012-09-24 | E-GEOD-37067 | biostudies-arrayexpress
UnknownDe novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Not available
S-EPMC7007577 | biostudies-literature
UnknownCommon variants near MC4R are associated with fat mass, weight and risk of obesity.
Not available
S-EPMC2669167 | biostudies-literature
UnknownKetamine, Etomidate, and Mortality in Emergency Department Intubations.
Not available
S-EPMC12706683 | biostudies-literature
Sort   by:  
 Page size