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MetabolomicsTranscriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models

Microorganisms can adopt a quiescent physiological condition which acts as a survival strategy under unfavourable conditions. Quiescent cells are characterized by slow or non-proliferation and deep down-regulation of processes related to biosynthesis. Although quiescence has been described mostly...

2022-02-23 | MTBLS4046 | MetaboLights
MetabolomicsAnalysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors

Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and adults in endemic areas. Gene regulation of ETEC during growth in vitro and in vivo needs to be further evaluated, and here we describe the full transcriptome and metabolome of ETEC dur...

2022-07-15 | MTBLS3540 | MetaboLights
TranscriptomicsCharacterizing the transcriptional adaptation of Staphylococcus aureus to stationary phase growth
Staphylococcus aureus is an important human pathogen that causes life-threatening infections, and is resistant to the majority of our antibiotic arsenal. This resistance is complicated by the observation that most antibacterial agents target actively growing cells, thus, proving ineffective against ...
ORGANISM(S): Staphylococcus aureus 
2016-05-18 | E-GEOD-77242 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bordetella pertussis from mid-log phase cultures diluted to two concentrations and grown beyond the log to stationary phase transition to determine growth phase-associated patterns of transcript abundance
B. pertussis mid-log phase cultures were diluted in modified Stainer-Scholte medium to a starting optical density at 600 nm of 0.03 to 0.05, then grown at 37 C with shaking until three hours beyond the log to stationary phase transition.
ORGANISM(S): Bordetella parapertussis 
2006-12-31 | E-TABM-100 | biostudies-arrayexpress
TranscriptomicsIdentification of Phx1 regulated genes during stationary phase in S.pombe.
Identification of Phx1 regulated genes during stationary phase in S.pombe.
ORGANISM(S): Schizosaccharomyces pombe 
2015-02-04 | E-MTAB-2285 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of three Bordetella bronchiseptica strains at three distinct phases of growth: mid-log phase, late-log phase, and late-stationary phase
Microarray analysis was performed to determine if the growth-dependent gene expression changes occurred on a global scale for B. bronchiseptica strains RB50, RB53, and RB54. For this analysis cDNA representing three distinct phases of growth: mid-log phase (15H), late-log phase (24H), and late-stati...
ORGANISM(S): Bordetella bronchiseptica 
2009-07-01 | E-MEXP-2015 | biostudies-arrayexpress
GenomicsXbp1 binding during log phase and stationary phase.
Xbp1 binding during log phase and stationary phase.
PRJNA868333 | ENA
TranscriptomicsCharacterization of PlcRa, a new PlcR-like regulator involved in oxidative stress response and cysteine metabolism during early stationary phase in Bacillus cereus
PlcR, the major virulence transcriptional regulator in the Bacillus cereus group belongs to the RNPP quorum sensor family and is activated through interaction with the secreted heptapeptide PapR7 used as a signalling molecule. We identified using modeling analysis a structural homologue of PlcR, Plc...
ORGANISM(S): Bacillus cereus ATCC 14579 
2012-12-14 | E-GEOD-30514 | biostudies-arrayexpress
TranscriptomicsStationary phase timecourse
Nine day glucose starvation stationary phase culture, exit and entry from quiescence
ORGANISM(S): Saccharomyces cerevisiae 
2005-04-15 | E-UMCU-12 | biostudies-arrayexpress
TranscriptomicsIdentification of genes regulated by gadE in E. coli O157:H7
Integrating laterally acquired virulence genes into the backbone regulatory network is important for the pathogenesis of Escherichia coli O157:H7, which has captured many virulence genes through horizontal transfer during evolution. GadE is an essential transcriptional activator of glutamate decarbo...
ORGANISM(S): Escherichia coli 
2010-05-18 | E-GEOD-13132 | biostudies-arrayexpress
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