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ProteomicsOptimal analytical strategies for sensitive and quantitative phosphoproteomics using TMT-based multiplexing
In large-scale quantitative mass spectrometry (MS)-based phosphoproteomics, isobaric labeling with tandem mass tags (TMTs) coupled with offline high-pH reversed-phase peptide chromatographic fractionation maximizes depth of coverage. To investigate to what extent limited sample amounts affects sensi...
ORGANISM(S): Homo sapiens (Human) 
2022-06-28 | PXD031277 | Pride
Tandem mass tags Phosphoproteomics Optimization High-ph fractionation Isobaric labeling 
ProteomicsAutomated high-throughput biological sex identification from archaeological human dental enamel using targeted proteomics
Biological sex is a key information for archaeological and forensic studies, which can be assessed in enamel using proteomics. However, the lack of a standard approach for fast and accurate sex identification limits the reach of proteomics applications. Here, we introduce a targeted proteomics-based...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD049326 | Pride
Forensics Prm Sex Palaeoproteomics Archaeology Enamel 
ProteomicsEnamel proteins reveal biological sex and intrataxon variability within Paranthropus robustus
The evolutionary relationships among extinct African hominin species are highly debated and largely unresolved, due in part to a lack of molecular data. Even within taxa, it is not always clear, based on morphology alone, whether ranges of variation are due to sexual dimorphism versus potentially un...
ORGANISM(S): Homo 
2025-06-09 | PXD040221 | Pride
Human evolution Sequence reconstruction Dental enamel Palaeoproteomics Enamel 
UnknownPregnancy denial and early infant development: a case-control observational prospective study.
Not available
S-EPMC6458722 | biostudies-literature
UnknownOverview of the pathological results and treatment characteristics in the first 1000 patients randomized in the SERC trial: axillary dissection versus no axillary dissection in patients with involved sentinel node.
Not available
S-EPMC6249981 | biostudies-literature
UnknownSentinel node involvement with or without completion axillary lymph node dissection: treatment and pathologic results of randomized SERC trial.
Not available
S-EPMC8501060 | biostudies-literature
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