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ProteomicsDeletion of matrix metalloproteinase-12 improves energy metabolism and brown adipose tissue function in mice prone to develop cardiometabolic disease
Matrix metalloproteinase-12 (MMP12) is a proinflammatory protein secreted by macrophages. We have previously demonstrated that the genetic deletion of MMP12 in a cardiometabolic mouse model (low-density lipoprotein receptor-deficient (LdlrKO) mice fed a high-fat, sucrose- and cholesterol-enriched di...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-19 | PXD063623 | Pride
Cold exposure Untargeted proteomics Bat Mitochondrial processes Ldlr-deficient mice Mmp12 
MetabolomicsProteomic and metabolomic profiling of extracellular vesicles produced by human gut archaea

Gastrointestinal bacteria interact with the host and each other through various mechanisms, including the production of extracellular vesicles (EVs). However, the composition and potential roles of EVs released by gut archaea are poorly understood. Here, we study EVs produced by four strains of h...

2025-07-01 | MTBLS12422 | MetaboLights
TranscriptomicsMorphological, genomic, and transcriptomic characterization of heterogeneity in chordoma cells
The classical sacrococcygeal chordoma tumor presents with a typical morphology of lobulated myxoid tumor tissue with cords, strands and nests of tumor cells consisting of small non-vacuolated cells, intermediate cells with a wide range of vacuolization and large heavily vacuolated (physaliferous) ce...
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-48779 | biostudies-arrayexpress
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