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TranscriptomicsExpression data from mouse lung treated with saline or bleomycin
Lung fibrosis represents the final common pathway of a variety of lung injuries, and it is characterized, independently of etiology, by the expansion of the fibroblast/myofibroblast population and by the abnormal accumulation of extracellular matrix (ECM) replacing normal functional parenchyma. In g...
ORGANISM(S): Mus musculus 
2013-03-11 | E-GEOD-42301 | biostudies-arrayexpress
TranscriptomicsDissection of human fibroblast populations by lung regions: genomic differences and functional pathway analysis
ABSTRACT Background: Primary human distal lung/parenchymal fibroblasts (DLF) exhibit a different phenotype from airway fibroblasts (AF), including the expression of high levels of alpha-SMA. The scope of the differences and the mechanisms driving them are unknown. We hypothesized that the distinct ...
ORGANISM(S): Homo sapiens 
2011-07-21 | E-GEOD-19362 | biostudies-arrayexpress
TranscriptomicsGenomic differences distinguish the myofibroblast phenotype of distal lung from airway fibroblasts
ABSTRACT Primary human distal lung/parenchymal fibroblasts (DLF) exhibit a different phenotype from airway fibroblasts (AF), including the expression of high levels of a-smooth muscle actin (a-SMA). The scope of the differences and the mechanisms driving them are unknown. To determine whether disti...
ORGANISM(S): Homo sapiens 
2011-07-21 | E-GEOD-27335 | biostudies-arrayexpress
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