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Calcific aortic valve disease (CAVD) is an slowly progressive calcification of heart valve which leads to aortic stenosis. The only existing treatment of CAVD is surgical replacment of calcified valve - development of anti-CAVD treatment is urgent task. For better understanding of molecular mechanis...
ORGANISM(S): Homo sapiens (Human) 
2022-10-21 | PXD032212 | Pride
During fundamental proteotranscriptomic analysis of human valve interstitial cells (VICs) osteogenic differentiation, we revealed ZBTB16 (PLZF) as one of the most upregulated proteins. Thus, to investigate its physiological role in VICs osteogenic differentiation we performed its overexpression by l...
ORGANISM(S): Homo sapiens (Human) 
2022-10-21 | PXD031572 | Pride
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