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TranscriptomicsCandidates for bile acid-dependent PPAR?-target genes in mouse intestinal cells
In addition to their role as a digestive detergent, bile acids have the ability to modulate the expression of genes. The intestinal content of cholic acids (CA) fluctuated in response to the daily feeding-fasting cycle; therefore, we hypothesized that the temporal accumulation of CA may affect the e...
ORGANISM(S): Mus musculus 
2015-08-01 | E-GEOD-55443 | biostudies-arrayexpress
TranscriptomicsDifferentially expressed genes between oncogene-introduced wild-type and Atf4-/- cells
During oncogenic transformation, cells acquire genetic mutations that override the normal mechanisms regulating cellular proliferation. Excessive expression of activating transcription factor 4 (ATF4) is often observed in mammalian malignant tumors. However, little is known about the role of ATF4 in...
ORGANISM(S): Mus musculus 
2011-08-16 | E-GEOD-31405 | biostudies-arrayexpress
TranscriptomicsInfluence of G0s2 gene knockdown on primary hepatocyte
Hepatocellular carcinoma is the third leading cause of cancer death worldwide, and it is necessary to elucidate the mechanism of hepatocarcinogenesis. Circadian clock systems have been related in cell cycle and carcinogenesis. In this study, hepatocarcinogenesis induced by DEN administration in mice...
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-39288 | biostudies-arrayexpress
Transcriptomics5/6 nephrectomy (5/6Nx) effect on the liver
Chronic renal failure (CRF) is associated with a decrease in drug metabolism. The present study investigated the repercussions of CRF on liver cytochrome P450 (CYPs), but the mechanisms have been little explored. On the other hand, the expression of several CYP genes exhibits circadian rhythm. Here ...
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-35135 | biostudies-arrayexpress
Transcriptomics5/6 nephrectomy (5/6Nx) effect on the brain
Chronic kidney disease (CKD) is a very important problem in global health treatment. CKD increases the disease risk of apoplexy, cardiac failure and cardiac infarction. In addition, neurological complications, including depression and restless legs syndrome, occur in almost all CKD patients; however...
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-35134 | biostudies-arrayexpress
ProteomicsTime-resolved analysis of vUNG phosphorylation
Time-resolved phosphoproteomic analysis of HEp-2 cells infected with wild type HSV-1(F)
ORGANISM(S): Cellular Organisms 
PXD055199 | JPOST Repository
ProteomicsMS-based determination of vUNG phosphorylation
Phosphoproteomic analysis of HEp-2 cells infected with wild type HSV-1(F)
ORGANISM(S): Cellular Organisms 
PXD043453 | JPOST Repository
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