Gene expression was measured in human KPL-1 breast cancer cell lines, both with and without knock-down of RAI2 by shRNA. Measurements of each condition were done in triplicates.
Single-cell RNA-seq libraries were generated from human PBMCs that were incubated with anti-HER2/CD3 TDB in the presence of KPL-4 cells. This dataset only contains the metadata and processed data. Raw data can be accessed via the EGA accession EGAS00001003734
Analysis of the role of PARP1 in gene transcription in cell lines with variable PARP1 activity. Total RNA was collected from MCF7, KPL-1, ZR7530, T47D, SKBR3, and Hs578T cells that had been treated with 10uM ABT-888 or DMSO for 48 hours.
Mutations in STK11/LKB1 in non-small cell lung cancer (NSCLC) are associated with poor patient responses to immune checkpoint blockade (ICB) and introduction of a Stk11/Lkb1 (L) mutation into murine lung adenocarcinomas driven by mutant Kras and Trp53 loss (KP) resulted in an ICB refractory syngenei...
