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ProteomicsIdentification and quantification of KPNA2 phosphorylation and interactome in response to hydrogen peroxide-induced oxidative stress
Karyopherin α 2 (KPNA2, importin α1) is involved in the nuclear import of proteins and participates in cellular processes and accumulates in the nucleus under cellular stresses including hydrogen peroxide-indeced oxidative stress via unknown mechanisms. We performed the immunoprecipitation assay and...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051121 | Pride
Npm1 Hydrogen peroxide Silac Phosphorylation Kpna2 
GenomicsIdentification of KPNA2 targets by RNA-Seq in osteosarcoma
Identification of KPNA2 targets by RNA-Seq in osteosarcoma
PRJNA850355 | ENA
UnknownKPNA2 promotes angiogenesis by regulating STAT3 phosphorylation.
Not available
S-EPMC9798605 | biostudies-literature
GenomicsRNA Binding protein KPNA2 promotes the progress of gastric cancer by regulating alternative splicing of related genes [RIP-seq]
RNA Binding protein KPNA2 promotes the progress of gastric cancer by regulating alternative splicing of related genes [RIP-seq]
PRJNA831667 | ENA
GenomicsRNA Binding protein KPNA2 promotes the progress of gastric cancer by regulating alternative splicing of related genes [RNA-seq]
RNA Binding protein KPNA2 promotes the progress of gastric cancer by regulating alternative splicing of related genes [RNA-seq]
PRJNA831668 | ENA
TranscriptomicsRNA Binding protein KPNA2 promotes the progress of gastric cancer by regulating alternative splicing of related genes [RNA-seq]
RNA binding proteins (RBPs) took a critical part in genome regulation. kpna2, as an essential member of the RBP family, was found to be highly expressed and associated with lymph node metastasis in gastric cancer (GC). Transcriptional sequencing data were used to find that KPNA2 primarily regulated ...
ORGANISM(S): Homo sapiens 
2024-08-02 | GSE201418 | GEO
TranscriptomicsRNA Binding protein KPNA2 promotes the progress of gastric cancer by regulating alternative splicing of related genes [RIP-seq]
RNA binding proteins (RBPs) took a critical part in genome regulation. kpna2, as an essential member of the RBP family, was found to be highly expressed and associated with lymph node metastasis in gastric cancer (GC). Transcriptional sequencing data were used to find that KPNA2 primarily regulated ...
ORGANISM(S): Homo sapiens 
2024-08-02 | GSE201419 | GEO
TranscriptomicsIdentification of KPNA2 targets by RNA-Seq in osteosarcoma
Despite recent advances, the poor outcomes in osteosarcoma suggest that novel therapeutic targets are needed. Karyopherin alpha 2 (KPNA2) is a nuclear import factor, which functions as an oncogene in many cancers. However, the role of KPNA2 in osteosarcoma and its mechanism of action are still uncle...
ORGANISM(S): Homo sapiens 
2023-06-16 | GSE206342 | GEO
GenomicsKPNA2 promotes osteosarcoma by regulating the alternative splicing of DDX3X mediated by YBX1
KPNA2 promotes osteosarcoma by regulating the alternative splicing of DDX3X mediated by YBX1
PRJNA1097489 | ENA
UnknownKPNA2 promotes renal cell carcinoma proliferation and metastasis via NPM.
Not available
S-EPMC8500977 | biostudies-literature
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