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TranscriptomicsDistinct gene signatures define pathogen- versus diet-induced atherosclerosis development
The goal of this study was to define gene expression profiles in aortic tissue in response to three pro-atherogenic stimuli at two time points. We identified gene expression profiles induced by oral P.gingivalis (Pg), intranasal C. pneumoniae (Cp), and Western diet (WD) at acute (1 day after last in...
ORGANISM(S): Mus musculus 
2015-01-06 | E-GEOD-60086 | biostudies-arrayexpress
ProteomicsMouse EL4 Tumor Proteome Comparison via LC-MSMS
The EL4 mouse tumor model is widely utilized within the field of oncology due to its ease of use and excellent response to chemotherapy, with tumors typically experiencing a reduction in mass of 70% following chemotherapy treatment with cyclophosphamide and etoposide for three days. As not much is k...
ORGANISM(S): Mus musculus (Mouse) 
2017-05-19 | PXD005592 | Pride
Chemotherapy Mouse tumor Tumor death El4 lymphoma Proteomics 
ProteomicsMouse Hepatic Lipid Droplet Proteome under Fasting and Re-Feeding
One of the key functions of the mammalian liver is lipid metabolism. During fasting, lipid storage in the liver increases in order to reserve and provide energy for cellular functions. Upon re-feeding, this reserve of lipids is rapidly depleted; this change is visible, as the organelles responsible ...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-25 | PXD005977 | Pride
Lipid droplet proteome Mouse Lipid metabolism Liver lds Lipid droplets Lc-ms/ms 
ProteomicsMouse Mammary Gland Morphogenic Differences with BAD 3SA Mutant
The identification of genes driving organ development is central to understanding which signaling pathways drive the pathogenesis of various diseases including cancer. This dataset depicts the proteomic changes observed in C57BL/6J mice expressing wild-type or 3SA-phospho mutant versions of the Bcl-...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-29 | PXD014347 | Pride
Breast Mammary morphogenesis Mouse Breast cancer Mammary gland Bad Lc-ms/ms 
ProteomicsSolvent Precipitation SP3 (SP4) enhances recovery for proteomics sample preparation without magnetic beads
Complete, reproducible extraction of protein material is essential for comprehensive and unbiased proteome analyses. A current gold standard is single-pot, solid-phase-enhanced sample preparation (SP3), in which organic solvent and magnetic beads are used to denature and capture protein aggregates, ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Drosophila melanogaster (Fruit fly) 
2022-08-01 | PXD032095 | Pride
Microparticles Proteomics Sample preparation Protein aggregation Contaminant removal Lc−ms/ms Protein precipitation 
UnknownThe Role of Elevated Branched-Chain Amino Acids in the Effects of Vertical Sleeve Gastrectomy to Reduce Weight and Improve Glucose Regulation.
Not available
S-EPMC7605275 | biostudies-literature
UnknownDevelopment, explanation, and presentation of the Physical Literacy Interventions Reporting Template (PLIRT).
Not available
S-EPMC9938627 | biostudies-literature
UnknownThe impact of highly effective modulator therapy on sinusitis and dysosmia in young children with cystic fibrosis: a prospective study protocol.
Not available
S-EPMC11726580 | biostudies-literature
UnknownFrequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders.
Not available
S-EPMC7050643 | biostudies-literature
ProteomicsTissue- and plasma-derived exosomal protein biomarkers define multiple human cancers
There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection. We investigated the proteomic profile of exosomes in 426 human samples from tissue explants (TE), plasma and other bodily fluids. Among traditional exosome markers, CD9, HSPA8, ALIX, HSP90AB1 represent ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-08-17 | PXD018301 | Pride
Exosomes  extracellular vesicles  proteomics  cancer  liquid biopsy  biomarkers  mass spectrometry  early cancer detection 
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