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TranscriptomicsGenome-wide analysis of the affect of neutrophil-derived microparticles on HUVECs
Analysis of the role of neutrophil-derived microparticles (MP) on gene expression modulation on HUVECs. This study shows that MP can influence gene expression on target cells, demonstrating that these MP are functional entities. Total RNA obtained from HUVECs treated with two different subsets of MP...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-25154 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression data from leukemia and breast cancer cell lines with/without treatment with microparticles
Microparticles (MPs) comprise the major source of systemic RNA including microRNA (miRNA), the aberrant expression of which appears to be associated with stage, progression and spread of many cancers. We have shown MPs to transfer multidrug resistance proteins accross both haematological and and non...
ORGANISM(S): Homo sapiens 
2012-06-08 | E-GEOD-34560 | biostudies-arrayexpress
ProteomicsQuantitative proteome analysis of plasma microparticles for characterization of HCV-induced hepatic cirrhosis and hepatocellular carcinoma
A quantitative label-free proteome analysis was performed using plasma samples from 22 hepatitis-C virus (HCV)-induced liver cirrhosis patients, 16 HCV-positive hepatocellular carcinoma patients with underlying cirrhosis and 18 healthy controls. Plasma microparticles (PMPS) were isolated using ultra...
ORGANISM(S): Homo sapiens (Human) 
2017-06-21 | PXD005777 | Pride
Plasma microparticles Liver cirrhosis Hepatitis c virus Label-free proteomics Hepatocellular carcinoma 
ProteomicsProtein aggregation capture on microparticles enables multi-purpose proteomics sample preparation
Universal proteomics sample preparation is challenging due to the high heterogeneity of biological samples. Here we describe a novel mechanism that exploits the inherent instability of denatured proteins for non-specific immobilization on microparticles by protein aggregation capture. To demonstrate...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-03-05 | PXD011677 | Pride
Microparticles Mass spectrometry Secretomics Proteomics Sample preparation Phosphoproteomics Magnetic beads 
GenomicsSmall RNA analysis from megakarocyte, platelet and their microparticles
Small RNA analysis from megakarocyte, platelet and their microparticles
PRJNA577688 | ENA
GenomicsMicroparticles globally reprogram the metabolism of Streptomyces albus
Microparticles globally reprogram the metabolism of Streptomyces albus
PRJNA648406 | ENA
ProteomicsCitrullinated proteins in platelets and platelets releasing microparticles may serve as a potential target of ACPA
To investigate the expression of peptidylarginine deiminase (PAD) enzymes and mining citrullination proteins in human platelets and platelets releasing microparticles (PRMs), and to determine whether these less-studied platelets associated citrullination proteins can be targeted by anti-citrullinate...
ORGANISM(S): Homo Sapiens 
2022-10-26 | PXD037743 |
GenomicsPlatelet pathogen reduction technologies alter the microRNA profile of platelet-derived microparticles
Platelet pathogen reduction technologies alter the microRNA profile of platelet-derived microparticles
PRJNA576924 | ENA
ProteomicsPROMIS-Quan: a novel proteomic method for plasma biomarker quantification
Unbiased proteomic analysis of plasma samples holds the promise to reveal clinically invaluable disease biomarkers. However the tremendous dynamic range of the plasma proteome has so far hampered the identification of such low abundant markers. To overcome this challenge we analyzed the plasma micro...
ORGANISM(S): Homo sapiens (Human) 
2015-01-28 | PXD001194 | Pride
Plasma Microparticles Super-silac Biomarkers 
ProteomicsQuantitative proteome analysis of plasma microparticles for characterization of HCV-induced hepatic cirrhosis and hepatocellular carcinoma
A quantitative label-free proteome analysis was performed using plasma samples from 22 hepatitis-C virus (HCV)-induced liver cirrhosis patients, 16 HCV-positive hepatocellular carcinoma patients with underlying cirrhosis and 18 healthy controls. Plasma microparticles (PMPS) were isolated using ultra...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-03-12 | MSV000085094 | MassIVE
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