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UnknownInterval-Based Secretomics Unravels Acute-Phase Response in Hepatocyte Model Systems.
Not available
S-EPMC9184749 | biostudies-literature
ProteomicsQuantitative secretomics during cardiomyogenic differentiation of human pluripotent stem cells
Cardiovascular diseases are a major cause of life-threatening burden around the world. The heart has a very low regeneration capacity and donor organs for transplantation are scarce. Therefore regeneration of lost myocardium with stem cell-derived cardiomyocytes (CMs) provides an attractive strategy...
ORGANISM(S): Homo sapiens (Human) 
2018-06-20 | PXD008554 | Pride
Hescs Cardiomyogenesis Secretomics Hipscs Lc-ms/ms 
ProteomicsParadoxical drug sensitization of lung cancer cells by stromal fibroblast-secreted IGF-binding proteins: Secretomics
Cancer-associated fibroblasts (CAFs) are an integral part of the tumor microenvironment often linked to drug resistance. Here, we report that CAFs, but not normal fibroblasts, can promote either resistance or unexpected drug sensitization of different lung cancer cells. Using unbiased secretomics, t...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD023626 | Pride
Lung cancer Secretomics Fibroblasts Targeted therapy 
ProteomicsInterval-based secretomics unravels the time-dependent acute phase response in hepatocyte model systems
Mass spectrometry based secretomics approaches preferentially utilize serum-free culture conditions to circumvent serum induced interference and enable sufficient analytical depth. However, this negatively affects a wide range of cellular functions and thus reduces the biological relevance. Moreover...
ORGANISM(S): Homo sapiens (Human) 
2022-05-04 | PXD027821 | Pride
Il1b Heparg Shedding Secretomics Liver Acute-phase response Interval-based secretomics Il6 Hepg2 
ProteomicsSecretomics of Jurkat cells treated with sanglifehrin A or cyclosporin A
Proteins secreted from Jurkat cells upon treatment with sanglifehrin A or cyclosporin A were profiled.
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD031010 | Pride
Secretomics Natural products 
UnknownSubcellular localization of extracytoplasmic proteins in monoderm bacteria: rational secretomics-based strategy for genomic and proteomic analyses.
Not available
S-EPMC3415414 | biostudies-literature
UnknownHarnessing microbial wealth for lignocellulose biomass valorization through secretomics: a review.
Not available
S-EPMC8256616 | biostudies-literature
UnknownComparative secretomics reveals novel virulence-associated factors of Vibrio parahaemolyticus.
Not available
S-EPMC4505105 | biostudies-literature
ProteomicsSecretomics and proteomics analysis of the Primary turmor cell and PC cells
Secretomics and proteomics analysis of the Primary turmor cell and PC cells
ORGANISM(S): Homo Sapiens 
PXD055731 |
ProteomicsBenchmarking of different methods for obtaining high quality secretomics data
The main drawback of secretome analyses are contaminating proteins derived from culture medium or proteins released from dying cells which are hard to distinguish from proteins actively secreted by cells. Therefore, several approaches have been applied allowing to remove contamination from secretome...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD018895 | Pride
Supernatant Secretomics Secreteome Benchmarking Conditioned medium 
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