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Haematopoietic stem cells (HSC) reside in locations within the bone marrow microenvironment (BMM) featuring a slightly higher extracellular calcium ion concentration [eCa2+]. HSC respond to [eCa2+] via the G-protein coupled calcium-sensing receptor (CaSR), but the role of CaSR for leukaemia and leuk...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD035937 | Pride
The G-protein coupled estrogen receptor GPER1 is thought to mediate rapid estrogen signaling at the membrane. Despite considerable efforts over the last years, its physiological ligand(s), interactors, and regulators are still very poorly understood. This is particularly problematic at a time when t...
ORGANISM(S): Homo sapiens (Human) 
2023-11-06 | PXD041943 | Pride
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