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ProteomicsProteomics analysis of the effects of Grammatophyllum speciosum extracts on macrophage cells
Grammatophyllum speciosum is a traditional plant with beneficial functionalities for health. G. speciosum extracts can inhibit collagenase and nitric oxide without cellular toxicity in keratinocytes. The extracts have shown potential for use and formulation as cosmeceutical ingredients. However, the...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-03 | PXD039206 | Pride
Lc-ms/ms Raw264.7 Traditional plant Cosmeceuticals 
ProteomicsTMT-10plex-based phosphoproteomics of bioactive compounds in A549 cells
We conducted a comprehensive screening of bioactive compounds sourced from natural products, specifically targeting those capable of inducing apoptosis while inhibiting tyrosine kinase activity. Our investigation encompassed a diverse range of compounds, including pure compounds, compound mixtures, ...
ORGANISM(S): Homo sapiens (Human) 
2024-03-13 | PXD050555 | Pride
Post translational modification Lc-ms/ms Phosphorylation Apoptosis Lung epidermal cells Isobaric mass tag Egfr 
ProteomicsProteomics analysis of octapeptide from Lingzhi mushroom with anti-tyrosinase and anti-oxidative activity
Study the effect of novel octapeptide isolated from Lingzhi mushroom on skin melanocyte cell (Mus Musculus) by gel-free based proteomics
ORGANISM(S): Mus musculus (Mouse) 
2022-08-11 | PXD017234 | Pride
Peptide Proteomics Anti-tyrosinase Anti-oxidative stress 
Proteomicsthe effects of the nanobody on SW480 cells using label-free proteomics approach
determine the effect of cell-penetrable nanobody (R9VH36) on cell viability and proteomic profile in EGFR-positive human colorectal cancer cell lines.
ORGANISM(S): Homo sapiens (Human) 
2022-04-24 | PXD033149 | Pride
Sw480 Peptides Gefitinib Egfr Nanobody Her2 
ProteomicsExploring the effect of citronellol on Candida albicans using proteomics appraoch
To explore the proteome profiles of Candida albicans exposed to citronellol. We used label-free proteomics approach.
ORGANISM(S): Candida albicans (Yeast) 
2022-05-04 | PXD030379 | Pride
Yeast Biomarker Lc-ms/ms 
ProteomicsUtilizing of quantitative proteomics to identify species-specific protein therapeutic target for treatment of leishmaniasis.
Identification of common Leishmania antigen proteins is important for practical purposes ranging from diagnostic to the development of a vaccine for the prevention of leishmaniasis. Moreover, we need to establish the potential drug targets that interrupt the replication and transmission of the patho...
ORGANISM(S): Leishmania donovani Ld 2001 
2022-05-20 | PXD026304 | Pride
Lc-ms/ms  orbitrap  antigenic molecules 
ProteomicsProteomics analysis of the effects of Grammatophyllum speciosum extracts on RAW 264.7 cells
Grammatophyllum speciosum is a traditional plant with beneficial functionalities for health. G. speciosum extracts can inhibit collagenase and nitric oxide without cellular toxicity in keratinocytes. The extracts have shown potential for use and formulation as cosmeceutical ingredients. However, the...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-27 | PXD038611 | Pride
Pca Quality control Macrophage Traditional plant Lc-ms/ms 
ProteomicsAnti-methicillin-resistant Staphylococcus aureus Peptides
Methicillin-resistant Staphylococcus aureus (MRSA) is a highly prioritized pathogen proposed by World Health Organization (WHO). It is listed to encourage researchers to search for effective antimicrobial agents. Previously, we isolated soil Brevibacillus sp. strain SPR19, which showed anti-MRSA act...
ORGANISM(S): Staphylococcus aureus 
2023-08-31 | PXD042035 | Pride
Lc-ms/ms Bacteria Biofilm 
ProteomicsAtmospheric and Room Temperature Plasma (ARTP) Mutagenesis Improved the Anti-MRSA Activity of Brevibacillus sp. SPR20
Brevibacillus sp. SPR20 produced potentially antibacterial substances against MRSA. The synthe-sis of these substances is controlled by their biosynthetic gene clusters. Several mutagenesis methods are used to overcome the restriction of gene regulations when genetic information is ab-sent. Atmosphe...
ORGANISM(S): Brevibacillus sp. 
2023-08-31 | PXD043954 | Pride
Atmospheric and room temperature plasma (artp)  anti-mrsa activity  brevibacillus sp.  muta-genesis  proteomic analysis  strain improvement. 
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