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TranscriptomicsBeta-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/beta-catenin signaling
To validate the suitability of two commonly used colorectal cancer cell lines, DLD1 and SW480, as model systems to study colorectal carcinogenesis, we treated these cell lines with beta-catenin siRNA and identified beta-catenin target genes using DNA microarrays. The list of identified target genes ...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-44097 | biostudies-arrayexpress
ProteomicsSW480 cells were analyzed with RDA23B IP by mass spectrometry
SW480 cells were coprecipitated with RDA23B antibody and analyzed by mass spectrometry
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD062847 | Pride
Sw480 rad23b ipmass 
TranscriptomicsMicroRNA profiling by array of human SW480 cells treated with resveratrol
The effects of resveratrol on miRNA populations in human SW480 cells were analyzed on miRNA microarrays
ORGANISM(S): Homo sapiens 
2010-12-09 | E-TABM-1034 | biostudies-arrayexpress
TranscriptomicsExpression data from SW480 cells with Gankyrin knockdown
We performed genome-wide screening using SW480 cells with Gankyrin knockdown on an Affymetrix gene expression array to identify the transcriptional targets of Gankyrin. Transcriptional profiling with samples from SW480 cells that were infected with control or gankyrin shRNA. Two condition experiment...
ORGANISM(S): Homo sapiens 
2013-02-04 | E-GEOD-44029 | biostudies-arrayexpress
TranscriptomicsExpression analysis of colorectal cancer cell line SW480 expressing FOXC2
Investigation of whole genome gene expression level changes in a colorectal cancer cell line SW480 expressing FOXC2, compared to the pBabe control cells. Genes associated with metastasis regulated by FOXC2 in colorectal cancer were analysed. The role of FOXC2 in breast cancer metastasis are furthe...
ORGANISM(S): Homo sapiens 
2014-07-02 | E-GEOD-58980 | biostudies-arrayexpress
TranscriptomicsHuman SW480 cells: Untreated vs H2O2 Treated
ChIP-on-chip tilling array comparing untreated human SW480 cells vs SW480 cells treated with 2mM H2O2 for 30min. Exposing cells to the reactive oxygen species, hydrogen peroxide, recruits DNA methyltransferase 1 (DNMT1) to damaged chromatin. DNMT1 becomes part of a complex(es) containing DNMT3B and...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-32382 | biostudies-arrayexpress
TranscriptomicsmRNA-seq of SW480 USP22 knockdown cells
This analysis identifies genes which are affected in SW480 cells upon siRNA-mediated USP22 knockdown
ORGANISM(S): Homo sapiens 
2019-12-05 | E-MTAB-8214 | biostudies-arrayexpress
TranscriptomicsSW480 Signaling Hub Inhibition
In tumor cells, stepwise oncogenic deregulation of signaling cascades induces alterations of cellular morphology and promotes the acquisition of malignant traits. Using a panel of small molecular inhibitors, we established associated gene expression signatures of key signaling hubs. SW480 cells were...
ORGANISM(S): Homo sapiens 
2011-06-03 | E-GEOD-29689 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profile between human colorectal cancer SW480 and SW620 cell line
Two isogenic human colorectal cancer cell lines (primary SW480 cell line and its lymph node metastatic variant SW620 cell line),as an in vitro metastatic model. We have demonstrated that SW620 cell line possesses high metastasis potential and SW480 cell linepossesses low metastatic potential. We w...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-72412 | biostudies-arrayexpress
ProteomicsSW480 N-terminal peptide analysis
N-terminal peptide analysis of SW480 cell line for Nt-formylation.
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD039053 | Pride
Sw480 N-terminome Human Inrich 
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