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TranscriptomicsTranscription profiling of human colon cancer cell line SW620 treated with docosahexaenoic acid
The human colon cancer cell line SW620 was supplemented with DHA (70 µM) or an equal volume of ethanol (control). Total RNA was isolated after 6 h and used for Affymetrix gene expression profiling.
ORGANISM(S): Homo sapiens 
2009-06-01 | E-MEXP-2010 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human HL60 cells treated with eicosapantaenoic acid (EPA) to investigate the effect on the signalling pathways involved in growth arrest/apoptosis
We investigated the effect of EPA on the signalling pathways involved in growth arrest/apoptosis in HL60 cells. EPA inhibited cell proliferation in HL60 cells in a dose dependent manner. Gene expression profiling of HL60 cells treated with EPA was performed by Affymetrix GeneChip. System and key mar...
ORGANISM(S): Homo sapiens 
2008-11-11 | E-MEXP-1389 | biostudies-arrayexpress
TranscriptomicsTimes series of cells synchronized by double thymidine block
HaCat cell cycle experiment: During the somatic cell cycle, DNA and epigenetic modifications in DNA and histones are copied to daughter cells. DNA replication timing is tightly regulated and linked to GC content, chromatin structure, andgene transcription, but how maintenance of histone modification...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-MTAB-454 | biostudies-arrayexpress
TranscriptomicsALKBH5 is a New Mammalian RNA Demethylase
N6-methyladenosine (m6A) is the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Here we report ALKBH5 as a new mammalian demethylase that oxidatively removes the m6A modification in mRNA in vitro and inside cells. This demethylation activity of ALKBH5 significantly...
ORGANISM(S): Mus musculus 
2013-02-15 | E-GEOD-40132 | biostudies-arrayexpress
UnknownA genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
Not available
S-EPMC2775843 | biostudies-literature
GenomicsA Genome-Wide Association Study of Lung Cancer Risk

Three genetic loci for lung cancer risk have been identified by genome-wide association studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not well established. We conducted a GWAS of lung cancer and its major histologic types genotyping 515,922 single n...

phs000336.v1.p1 | EGA
UnknownIdentification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia.
Not available
S-EPMC4635669 | biostudies-literature
UnknownRare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.
Not available
S-EPMC4074058 | biostudies-literature
UnknownTargeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Not available
S-EPMC7708037 | biostudies-literature
UnknownLung cancer susceptibility locus at 5p15.33.
Not available
S-EPMC2748187 | biostudies-literature
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