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TranscriptomicsTranscriptional profiling by array in rat of age-dependent gene expression in sensorimotor cortex following spinal cord injury
In this study, we investigated the extent and nature of the difference between the dynamic cortical gene expression profiles of aged (22-month-old) and young (2-month-old) rats following thoracic corticospinal tract (CST) transection and whether the anti-scarring-treatment (AST)-induced regeneration...
ORGANISM(S): Rattus norvegicus 
2012-01-15 | E-MTAB-794 | biostudies-arrayexpress
TranscriptomicsClassifications within Molecular Subtypes Enables Identification of BRCA1/BRCA2 Mutation Carriers by RNA Tumor Profiling
Pathogenic germline mutations in BRCA1 or BRCA2 are detected in less than one third of families with a strong history of breast cancer. It is therefore expected that mutations still remain undetected by currently used screening methods. In addition, a growing number of BRCA1/2 sequence variants of u...
ORGANISM(S): Homo sapiens 
2013-06-28 | E-GEOD-40115 | biostudies-arrayexpress
UnknownControl of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors.
Not available
S-EPMC3549986 | biostudies-literature
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
UnknownSARS-CoV-2 vaccination and ITP in patients with de novo or preexisting ITP.
Not available
S-EPMC8483984 | biostudies-literature
TranscriptomicsRNA Profiles Reveals Familial Aggregation of Molecular Subtypes in non-BRCA1/2 Breast Cancer Families
In more than 70% of families with a strong history of breast and ovarian cancers, pathogenic mutation in BRCA1 or BRCA2 cannot be identified, even though hereditary factors are expected to be involved. It has been proposed that tumors with similar molecular phenotypes also share similar pathophysiol...
ORGANISM(S): Homo sapiens 
2015-08-01 | E-GEOD-49481 | biostudies-arrayexpress
TranscriptomicsInhibition of histone deacetylase activity interferes with innate immune responses and protects from severe sepsis
Sensing of microbial products by innate immune cells skew their transcriptional program to optimize anti-microbial defences. Chromatin remodeling by histone deacetylases (HDACs) plays a fundamental role in tailoring gene expression. HDAC inhibitors are among the most promising anti-cancer drugs and ...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-22409 | biostudies-arrayexpress
UnknownBreast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores.
Not available
S-EPMC8755508 | biostudies-literature
UnknownAn original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers.
Not available
S-EPMC4478717 | biostudies-literature
UnknownAssociation of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.
Not available
S-EPMC4537700 | biostudies-literature
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