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ProteomicsProteomic analysis of lysine 2-hydroxyisobutyryl in SLE reveals protein modification alteration in Complement and coagulation cascades and Platelet activation pathways
Post-translational modifications (PTMs) are considered to be an important factor in the pathogenesis of SLE. Lysine 2-hydroxyisobutyryl (Khib), as an emerging post-translational modification of proteins, is involved in some important biological metabolic activities. We compared the Khib levels of SL...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD040218 | Pride
Human Lysine 2-hydroxyisobutyryl Pbmc Sle 
MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
MetabolomicsTranscriptomic and metabolomic analysis of liver cirrhosis
Liver cirrhosis is one of the leading causes of decreased life expectancy worldwide. However, the molecular mechanisms underlying the development of liver cirrhosis remain unclear. In this study, we performed a comprehensive analysis using transcriptome and metabolome sequencing to explore the genes...
2024-08-07 | MTBLS5665 | MetaboLights
UnknownPseudomonas aeruginosa pyocyanin modulates mucin glycosylation with sialyl-Lewis(x) to increase binding to airway epithelial cells.
Not available
S-EPMC4864173 | biostudies-literature
UnknownGold nanoparticle-based immunochromatographic assay for detection Pseudomonas aeruginosa in water and food samples.
Not available
S-EPMC7985707 | biostudies-literature
UnknownDesipramine reverses remote memory deficits by activating calmodulin-CaMKII pathway in a UTX knockout mouse model of Kabuki syndrome.
Not available
S-EPMC11529476 | biostudies-literature
UnknownLiver X receptors agonist promotes differentiation of rat bone marrow derived mesenchymal stem cells into dopaminergic neuron-like cells.
Not available
S-EPMC5787491 | biostudies-literature
ProteomicsNanonets collect cancer secretome from pericellular space
Identifying novel cancer biomarkers is important for early cancer detection as it can reduce mortality rates. The cancer sectretome, the collection of all macromolecules secreted by a tumor cell, alters its composition compared to normal tissue, and this change plays an important role in the observa...
ORGANISM(S): Homo sapiens (Human) 
2016-04-27 | PXD003924 | Pride
Human Cancer Secretome 
UnknownPrognostic role of lymphocyte-to-monocyte ratio in pancreatic neuroendocrine neoplasms.
Not available
S-EPMC7159258 | biostudies-literature
UnknownUltrasensitive monitoring of SARS-CoV-2-specific antibody responses based on a digital approach reveals one week of IgG seroconversion.
Not available
S-EPMC9476360 | biostudies-literature
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