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ProteomicsRegulation of host RNA splicing in Mycobacterium tuberculosis infected macrophages
Alternative splicing is a key event which enables us to generate protein diversity from a limited set of genetic information. Previously we have shown that Mycobacterium tuberculosis (Mtb) which primarily infects the host macrophages and causes genome-wide transcriptional reprogramming in the host a...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2025-06-17 | PXD039671 | Pride
Rna splicing Mycobacterium tuberculosis : host-pathogen interaction Spliceosome 
UnknownMesenchymal stem cells offer a drug-tolerant and immune-privileged niche to Mycobacterium tuberculosis.
Not available
S-EPMC7297998 | biostudies-literature
TranscriptomicsRNAi knock down of PLC gamma 2, CaMKII, PKC delta and Pyk2 in mouse B cell line A20 after stimulation by anti-IgG to examine the adaptation response of the BCR-dependent intracellular signaling network
We examined the adaptation response of the BCR-dependent intracellular signaling network, to targeted perturbations induced through siRNA-mediated depletion of select signaling intermediates. The robustness of this network was found to derive from the fact that its constituent nodes displayed graded...
ORGANISM(S): Mus musculus 
2008-02-01 | E-TABM-360 | biostudies-arrayexpress
UnknownPrognostic role of anemia in heart failure with preserved ejection fraction: A systematic review and meta-analysis.
Not available
S-EPMC8424263 | biostudies-literature
ProteomicsMRM quantification of circulating CFP-10 in TB patients
Liquid chromatography coupled mass spectrometry (LC-MS) operating in targeted mass spectrometry (MS) including multiple reaction monitoring (MRM) mode is an accurate analytical method. Integrating with nanoelectrospray-tandem MS (NanoES-MS/MS) and immunoprecipitation (IP), it becomes a promising met...
ORGANISM(S): Mycobacterium Tuberculosis 
2022-04-14 | PXD021150 | panorama
TranscriptomicsIdentification of genes differentially regulated upon infection of Thp-1 cells with H37Rv
Perturbation of host physiology by intracellular Mycobacterium tuberculosis (H37Rv) can be reflected by changes in gene expression pattern of host genes. Total RNA was isolated from PMA differentiated uninfected cells or cells infected with H37Rv for 16, 48 or 90 hours and gene expression profile wa...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-19052 | biostudies-arrayexpress
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