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Metabolomics1H NMR Metabolomics Reveals Association of High Expression of Inositol 1, 4, 5 Trisphosphate Receptor and Metabolites in Breast Cancer Patients
1H NMR is used to detect alterations in metabolites and their linkage to metabolic processes in a number of pathological conditions including breast cancer. Inositol 1, 4, 5 trisphosphate (IP3R) receptor is an intracellular calcium channel known to regulate metabolism and cellular bioenergetics. Its...
2017-07-18 | MTBLS326 | MetaboLights
ProteomicsN Gene TurboID (Group1 -p50)
Nicotiana benthamiana plants were infiltrated with three different constructs: 1) N-TurboID-3HA 2) NTIR-TurboID-3HA or 3) Citrine-TurboID-3HA. N-TurboID is the full length N-gene fused to TurboID, NTIR-Turbo is the TIR domain of the N-gene fused to turboID, and Citrine-TurboID is the control constru...
ORGANISM(S): Nicotiana Benthamiana (ncbitaxon:4100) 
2018-10-10 | MSV000083018 | MassIVE
ProteomicsN Gene TurboID (Group2 +p50)
Nicotiana benthamiana plants were infiltrated with three different constructs: 1) N-TurboID-3HA 2) NTIR-TurboID-3HA or 3) Citrine-TurboID-3HA. N-TurboID is the full length N-gene fused to TurboID, NTIR-Turbo is the TIR domain of the N-gene fused to turboID, and Citrine-TurboID is the control constru...
ORGANISM(S): Nicotiana Benthamiana (ncbitaxon:4100) 
2018-10-10 | MSV000083019 | MassIVE
TranscriptomicsEndogenous DAF-16 genome-wide recruitment under low Insulin signalling condition in Caenorhabditis elegans
In order to understand the complexity of gene regulation downstream of IIS, we did RNA-seq in mixed culture in wild-type, daf-2(e1370), daf-16(mgDf50);daf-2(e1370) and daf-2(e1370);daf-12(m20 and correlated it with ChIP-seq data RNA-seq profile of different mutants in mix stage
ORGANISM(S): Caenorhabditis elegans 
2016-03-01 | E-GEOD-67975 | biostudies-arrayexpress
UnknownMachine intelligence-driven framework for optimized hit selection in virtual screening.
Not available
S-EPMC9306080 | biostudies-literature
TranscriptomicsActivation of TGF-beta pathway by areca nut constituents: A possible cause of Oral submucous fibrosis.
To understand the role of areca nut constituents in manifestation of Oral submucous fibrosis, we studied gene expression profile in epithelial cells following areca nut water extract treatment. A comaprison with TGF-beta induced gene expression changes were performed as epithelial cells were predict...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-38227 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of breast cancer cells with Insulin like growth factor binding protein 2 (IGFBP2) knockdown
The study was carried out to identify the genes regulated upon IGFBP2 modulation in breast cancer. This will help to understand the molecular targets and biological pathways targeted by IGFBP2 in breast cancer. C5 (Cy5) Vs. Vector(Cy3), C5 (Cy5) Vs. Vector(Cy3), C12 (Cy5) Vs. Vector(Cy3), C12 (Cy5) ...
ORGANISM(S): Homo sapiens 
2013-09-06 | E-GEOD-40682 | biostudies-arrayexpress
TranscriptomicsRole of areca nut induced TGF-β and epithelial mesenchymal interaction in pathogenesis of precancerous Oral submucous fibrosis
To understand the role of areca nut and TGF-β induced gene expression changes in fibroblasts and its contibution in the manifestation of Oral submucous fibrosis, we studied gene expression profile in primary human gingival fibroblast (hGF) cells following treatment with areca nut, TGF-β and both tog...
ORGANISM(S): Homo sapiens 
2015-07-06 | E-GEOD-59414 | biostudies-arrayexpress
TranscriptomicsEffect of Epigallocatechin gallate (EGCG), a green tea ployphenol, on estrogen regulated genes in breast cancer cell line MCF7.
Epigallocatechin gallate (EGCG), the major green tea polyphenol, has been a subject of global interest as a potential chemopreventive or chemotherapeutic supplement for breast cancer. While on one hand epidemiological studies suggest inverse correlation between green tea consumption and breast cance...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-56245 | biostudies-arrayexpress
ProteomicsSoDA-PAL Protein Profiling Proteomics of Sorgoleone Catabolizing Microbial Isolate Acinetobacter pittii SO1
Photoaffinity probe-based protein labeling of microbial isolate Acinetobacter pittii SO1 (NCBITAXON:48296), isolated from the sorghum rhizosphere that can utilize sorgoleone as a sole carbon source in order to identify proteins that bind sorgoleone. Photoaffinity labeling of A. pittii lysates using ...
ORGANISM(S): Acinetobacter Pittii (ncbitaxon:48296) 
2023-05-18 | MSV000091986 | MassIVE
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