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Methylation analysis of 12 corresponding pairs of tumor endothelial cells (TECs) and normal endothelial cells (NECs) isolated from human colorectal carcinoma (CRC) patients with different prognostic tumor microenvironments (TMEs: Th1-TME vs Control-TME): High and low GBP-1 expression in the tumors d...
ORGANISM(S): Homo sapiens 
Resveratrol has been reported to improve metabolic function in metabolically-abnormal rodents and humans, but has not been studied in non-obese people with normal glucose tolerance. We conducted a randomized, double-blind, placebo-controlled trial to evaluate the metabolic effects of 12 weeks of re...
ORGANISM(S): Homo sapiens 
Proteomic profiling of canine fibrosarcomas and adjacent unaffected peritumoral tissue using laser-capture microdissected FFPE tissue
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2023-03-11 | PXD029338 | Pride
Resveratrol is a naturally occurring compound that profoundly affects energy metabolism and mitochondrial function and serves as a calorie restriction mimetic, at least in animal models of obesity. Here we treated 10 healthy, obese men with placebo and 150 mg/day resveratrol in a randomized double-b...
ORGANISM(S): Homo sapiens 
Cancer-associated stroma (CAS) profoundly influences development and progression of tumours including mammary carcinoma (mCA). Spontaneous canine simple mCA represent relevant models of human mCA, notably also with respect to CAS reprogramming. While transcriptomic changes in CAS of mCA are well des...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2021-03-30 | PXD023023 | Pride
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