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TranscriptomicsIsoform diversity and regulation in peripheral and central neurons revealed through RNA-Seq
To fully understand cell type identity and function in the nervous system there is a need to understand neuronal gene expression at the level of isoform diversity. Here we applied Next Generation Sequencing of the transcriptome (RNA-Seq) to purified sensory neurons and cerebellar granular neurons (C...
ORGANISM(S): Mus musculus 
2012-01-17 | E-GEOD-33343 | biostudies-arrayexpress
TranscriptomicsRelationship between nucleosome positioning and DNA methylation: ChIP-chip
Nucleosomes compact and regulate access to DNA in the nucleus, and are composed of approximately 147 bases of DNA wrapped around a histone octamer1, 2. Here we report a genome-wide nucleosome positioning analysis of Arabidopsis thaliana utilizing massively parallel sequencing of mononucleosomes. By...
ORGANISM(S): Arabidopsis thaliana 
2010-05-28 | E-GEOD-21818 | biostudies-arrayexpress
GenomicsRelationship between nucleosome positioning and DNA methylation: Bisulfite-Seq, ChIP-Seq, and Mnase-Seq
Nucleosomes compact and regulate access to DNA in the nucleus, and are composed of approximately 147 bases of DNA wrapped around a histone octamer. Here we report a genome-wide nucleosome positioning analysis of Arabidopsis thaliana utilizing massively parallel sequencing of mononucleosomes. By com...
ORGANISM(S): Homo sapiens 
2010-05-29 | E-GEOD-21821 | biostudies-arrayexpress
UnknownStudy protocol of a randomized controlled trial comparing two linkage models for HIV prevention and treatment in justice-involved persons.
Not available
S-EPMC9013109 | biostudies-literature
TranscriptomicsWB001A: Genome-wide analysis reveals NRP1 as a critical HIF1-E2F7 target gene in the regulation of motor neuron guidance in vivo
In this study, we explored the existence of a transcriptional network co-regulated by E2F7 and HIF1α, as we show that expression of E2F7, like HIF1α, is induced in hypoxia, and because of the previously reported ability of E2F7 to interact with HIF1α. Our genome-wide analysis uncovers a transcrip...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-66750 | biostudies-arrayexpress
UnknownAdjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer.
Not available
S-EPMC5538020 | biostudies-literature
UnknownA methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparison.
Not available
S-EPMC12504109 | biostudies-literature
UnknownExploring the genetics of lithium response in bipolar disorders.
Not available
S-EPMC11169116 | biostudies-literature
UnknownImmunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder.
Not available
S-EPMC10350128 | biostudies-literature
UnknownCombining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.
Not available
S-EPMC8630000 | biostudies-literature
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